阿尔茨海默病是一种不可逆的、与年龄相关的神经退行性疾病，目前仍然是一种无法治愈的疾病。自噬可以通过促进β-淀粉样肽清除、降低Tau蛋白磷酸化发挥神经保护作用。中药活性成分可以通过自噬诱导阶段、自噬泡延伸阶段、自噬体加工阶段以及线粒体自噬干预阿尔茨海默病。探讨中药活性成分通过调控自噬干预阿尔茨海默病的研究进展，以期为中药治疗阿尔茨海默病的临床应用提供参考。

Alzheimer’s disease is an irreversible, age-related neurodegenerative disease that is currently still an incurable disease. Autophagy can play neuroprotective role by promoting the clearance of amyloid β and reducing Tau protein phosphorylation. Active ingredients of traditional Chinese medicine can intervene in Alzheimer's disease through autophagy induction stage, autophagosome extension stage, autophagosome processing stage, and mitochondrial autophagy. This article explores the research progress of active ingredients in traditional Chinese medicine intervening in Alzheimer's disease by regulating autophagy, in order to provide reference for the clinical application of traditional Chinese medicine in treatment of Alzheimer's disease.

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