心肌梗死已成为威胁人类健康的重要疾病之一。丹参酮Ⅱ_A是从丹参中提取的有效成分，具有多种药理活性，可通过舒张血管、延缓心肌纤维化进程、抑制心肌细胞凋亡、减轻炎症反应、降低氧化应激反应、促进新生血管形成发挥治疗心肌梗死的作用。综述了丹参酮Ⅱ_A改善心肌梗死的药理作用研究进展，希望为丹参酮Ⅱ_A的临床应用提供参考。

Myocardial infarction has become one of the important diseases threatening human health. Tanshinone II_A is an active ingredient extracted fromSalviae Miltiorrhizae Radix etRhizoma, with various pharmacological activities. Tanshinone II_A can treat myocardial infarction by dilating blood vessels, delaying the progression of myocardial fibrosis, inhibiting myocardial cell apoptosis, reducing inflammatory response, lowering oxidative stress response, and promoting neovascularization. This article reviews the pharmacological research progress of tanshinone II_A in improving myocardial infarction, hoping to provide reference for the clinical application of tanshinone II_A.

R285

重庆市自然科学基金面上项目（CSTB2024NSCQ-MSX1301）