目的 统计宁夏回族自治区宁安医院2021—2024年第二类精神药品使用情况，分析变化趋势，促进医院第二类精神药品合理使用。方法 采用回顾性分析收集宁夏回族自治区宁安医院2021—2024年第二类精神药品的销售金额和使用量，计算第二类精神药品的用药频度（DDDs），限定日费用（DDC）以药品的排序比（B/A）。结果 2021—2024年，医院第二类精神药品销售金额呈现逐渐增长趋势，奥沙西泮、扎来普隆、劳拉西泮（1 mg）的销售金额及排序始终位居前列；第二类精神药品的DDDs总体呈逐年增长趋势，右佐匹克隆、艾司唑仑、阿普唑仑始终位于前列，右佐匹克隆（3 mg）、扎来普隆分散片DDDs下降明显；第二类精神药品的DDC及排序基本平稳，奥沙西泮、扎来普隆、地佐辛注射液DDC较高，排名始终在前3位；酒石酸唑吡坦（5 mg）、佐匹克隆片、苯巴比妥片、地西泮片、氯硝西泮片（0.5 mg）地佐辛注射液的B/A均接近1。结论 宁夏回族自治区宁安医院第二类精神药品的使用仍存在不合理现象，继续加强第二类精神药品的管理和监督，确保患者用药安全、有效、经济。

Objective To analyze the usage of class Ⅱ psychotropic drugs in Ningxia Hui Autonomous Region Ning’an Hospital from 2021 to 2024, analyze the changing trend, and promote the rational use of class Ⅱ psychotropic drugs in the hospital. Methods A retrospective analysis was conducted to collect the sales amount and usage of class Ⅱ psychotropic drugs in Ningxia Hui Autonomous Region Ning’an Hospital from 2021 to 2024. The frequency of use (DDDs) of class Ⅱ psychotropic drugs was calculated, and the daily cost (DDC) was determined based on the drug ranking ratio (B/A). Results From 2021 to 2024, The sales amount of class Ⅱ psychotropic drugs in hospitals is gradually increasing, with sales amount and ranking of oxazepam, zaleplon, and lorazepam (1 mg) consistently ranking among the top; The DDDs of the class Ⅱ psychotropic drugs have shown an overall increasing trend year by year, with levozopiclone, estazolam, and alprazolam consistently ranking among the top. The DDDs of levozopiclone (3 mg) and zaleplon dispersible tablets have decreased significantly. The DDC and ranking of the class Ⅱ psychotropic drugs are basically stable, with oxalazepam, zaleplon, and dizocin injection having higher DDC and consistently ranking in the top 3. The B/A ratios of zolpidem tartrate (5 mg), zopiclone tablets, phenobarbital tablets, diazepam tablets, clonazepam tablets (0.5 mg), and dizoxin injection are all close to 1. Conclusion There are still unreasonable phenomena in the use of class Ⅱ psychotropic drugs in Ningxia Hui Autonomous Region Ning’an Hospital. We will continue to strengthen the management and supervision of class Ⅱ psychotropic drugs to ensure the safety, effectiveness, and economy of patient medication.

R971

宁夏回族自治区重点研发计划项目资助（2024BEG02026）