橙花叔醇是一种倍半萜类天然产物，具有多种药理作用，对神经损伤具有良好的保护特性。橙花叔醇发挥神经保护作用机制包括抑制氧化应激、抑制炎症反应、改善神经递质和抑制细胞凋亡、调节细胞色素P450酶活性。总结了橙花叔醇的神经保护作用机制的研究进展，为橙花叔醇在神经系统疾病治疗中的应用提供理论依据。

Nerolidol is a natural sesquiterpene product with various pharmacological effects, and has good protective properties against nerve damage. The neuroprotective mechanism of nerolidol includes inhibiting oxidative stress, suppressing inflammatory response, improving neurotransmitters and preventing cell apoptosis, and regulating cytochrome P450 enzyme activity. This article summarizes the research progress on neuroprotective mechanism of nerolidol, providing a theoretical basis for its application in treatment of neurological diseases.

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国家自然科学基金资助项目（81870576）；国家自然科学基金地区科学基金项目（2023AFD111）