目的 建立二甲双胍药物利用评价标准，评价临床使用的合理性。方法 以盐酸二甲双胍片和盐酸二甲双胍缓释片药品说明书为基础，参考相关指南和专家共识，建立评价标准。利用AHP加权TOPSIS法评价医院2023年1月～12月242份病例二甲双胍使用的合理性。结果 242份病例中，74份使用合理（占比30.58%）；153份使用基本合理（占比63.22%）；15份使用不合理（占比6.20%）。结论 建立的二甲双胍药物利用评价标准和AHP加权TOPSIS法可用于二甲双胍的合理性评价，评价结果显示该药的使用基本合理。

Objective To establish the evaluation criteria of metformin drug utilization and evaluate the rationality of clinical use. Methods Based on the drug instructions of Metformin Hydrochloride Tablets and Metformin Hydrochloride Sustained-release Tablets, the evaluation criteria were established with reference to relevant guidelines and expert consensus. The rationality of using metformin in 242 patients in January to December 2023 was evaluated by AHP weighted TOPSIS method. Results Among 242 cases, metformin was used reasonably in 74 cases (30.58%). The use of metformin was reasonable in 153 cases (63.22%). The use of metformin was unreasonable in 15 cases (6.20%). Conclusion The established evaluation criteria and AHP weighted TOPSIS method can be used to evaluate the rationality of metformin, and the evaluation results show that the use of metformin is basically reasonable.

R977

安徽省卫生健康科研项目（AHWJ2023BAc10045）