结肠炎是多种因素引起的结肠炎症性病变,发病率逐年上升,病程冗长,有并发结肠癌风险。黄芩苷是黄芩中重要的黄酮类化合物之一,可通过降低炎症反应、抗氧化应激反应、调节细胞凋亡、调节肠道菌群、调节细胞自噬等多种途径发挥抗结肠炎作用。归纳了黄芩苷防治结肠炎的作用机制研究进展,为黄芩苷的临床应用提供参考。

Colitis is a pathological change of colitis caused by many factors. Its incidence rate is increasing year by year, its course is long, and there is a risk of colon cancer. Baicalin is one of the important flavonoid compounds in Scutellariae Radix. Baicalin can play a preventive and therapeutic role in colitis by reducing inflammatory action, antioxidant stress action, regulating cell apoptosis, regulating intestinal microbiota, and regulating cell autophagy. This article summarizes the research progress on the mechanism of baicalin in prevention and treatment colitis, providing reference for the clinical application of baicalin.

R285;R975

潍坊市科技发展计划（软科学）项目（2023RKX101）