Benign prostatic hyperplasia is a common disease affecting the health of male urinary system. Curcumin is a diketone compound extracted from Curcumae Longae Rhizoma. It has many effects and is widely used in treatment of many diseases. Curcumin can inhibit prostatic hyperplasia and reduce the inflammatory reaction of prostatitis in a variety of ways, such as inhibit activation of NF-κB signaling pathway and secretion of inflammatory factors, promote apoptosis of prostate stromal cells, inhibit the epithelialmesenchymal transformation process of prostate cells, inhibit the expression of growth factors in prostate tissue, and other multiple pathways inhibit prostate hyperplasia and alleviate the inflammatory response of prostatitis. This article reviews the mechanism of curcumin in prevention and treatment of benign prostatic diseases, and provides a reference for the clinical application of curcumin.