目的 分析新疆医科大学附属肿瘤医院门诊麻醉药品的使用现状,为促进合理用药提供参考依据,促进癌症镇痛药物合理使用和科学规范管理。方法 收集2019—2022年新疆医科大学附属肿瘤医院门诊患者麻醉药品用药相关数据,对麻醉药品的处方数量、总消耗量、销售总金额、用药频度(DDDs)、限定日费用(DDC)、排序比(B/A)等进行数据分析。结果 2019—2022年新疆医科大学附属肿瘤医院门诊麻醉药品共涉及12个品规。盐酸羟考酮缓释片(10 mg)、盐酸吗啡片的处方量较多;麻醉药品的总消耗量显现逐年递减现象,盐酸羟考酮缓释片(40 mg)和硫酸吗啡缓释片(30 mg)总体用药量较多;销售金额总体上出现递增趋势,其中盐酸羟考酮缓释片(40 mg)与盐酸吗啡缓释片(30 mg)销售金额连续4年位居前3名,并且2者的DDDs连续3年排在前3名。结论 新疆医科大学附属肿瘤医院门诊患者麻醉药品总消耗量逐渐减少,销售金额逐年增长,麻醉药品的使用基本合理,管理方式科学有序符合标准。但是,仍需加强临床规范化用药,药师需要进一步提高业务能力并加强监督和干预,倡导麻醉药品个体化用药。

Objective To analyze the current situation of outpatient narcotic drugs in Affiliated Tumor Hospital of Xinjiang Medical University, to provide a reference for promoting rational drug use, and promote the rational use and scientific and standardized management of cancer analgesic drugs.Methods The outpatient narcotic medication data of Affiliated Tumor Hospital of Xinjiang Medical University from 2019 to 2022 were collected on the prescription quantity, total consumption, total sales amount, medication frequency(DDDs), limited daily cost(DDC), and ranking ratio(B/A).Results There were 12 outpatient narcotic drugs in Affiliated Tumor Hospital of Xinjiang Medical University from 2019 to 2022. Oxycodone Hydrochloride Sustained Release Tablets(10 mg) and Morphine Hydrochloride Tablets were more prescribed. The total consumption of narcotic drugs has been decreasing year by year. The total dosage of Oxycodone Hydrochloride Sustained-release Tablets(40 mg) and Morphine Sulfate Sustained-release Tablets(30 mg)was higher. The consumption sum of Oxycodone Hydrochloride Sustained-release Tablets(40 mg) and Morphine Hydrochloride Sustained-release Tablets(30 mg) ranked the top 3 in terms of consumption sum for 4 consecutive years, and the DDDs of these two tablets ranked the top 3 for 3 consecutive years.Conclusion The total consumption of narcotic drugs in outpatients of Affiliated Tumor Hospital of Xinjiang Medical University has gradually decreased, the sales amount increases year by year, the use of narcotic drugs is basically reasonable, and the management mode is scientific and orderly. However, it is still necessary to strengthen standardized clinical drug use, and pharmacists need to further improve their professional ability, strengthen supervision and intervention, and advocate individualized drug use of narcotic drugs.

R971

新疆自治区自然科学基金资助项目(2022D01C286)