目的 分析漯河市中心医院西城分院2019—2022年抗精神病药物的用药情况,为临床合理用药提供参考。方法 采用回顾性研究方法,对漯河市中心医院西城分院2019—2022年抗精神病药物的销售金额、用药频度(DDDs)、排序比(B/A)和日均费用(DDC)进行统计分析。结果 抗精神病药物的销售金额先增长后下降,非典型抗精神病药物销售金额占比始终较高;DDDs呈逐年上涨趋势,阿立哌唑和奥氮平一直占据销售金额和DDDs的前2位;DDC值变化较大,奥氮平、氨磺必利等高价品种的DDC值下降明显,而一些低价品种DDC则略有上涨;氨磺必利、奥氮平和阿立哌唑的B/A值变动较大,2022年所有抗精神病药物B/A值均接近1。结论 该院抗精神病药的使用情况较为合理,临床治疗以疗效好、不良反应少的非典型抗精神病药为主,特别是阿立哌唑和奥氮平,使用频度最高。氨磺必利和喹硫平用药频度增幅明显。

Objective To analyse the utilization of antipsychotic drugs in Xicheng Branch of Luohe Central Hospital from 2019 to 2022, so as to provide reference for rational usage of medication in clinic. Method The method of retrospective study was used to conduct statistic analysis on the sales amount, medication frequency(DDDs), drug sequence ratio(B/A) and daily drug cost(DDC) of antipsychotic drugs in Xicheng Branch of Luohe Central Hospital from 2019 to 2022.Results The sales amount of antipsychotic drugs of the hospital first increased and then decreased, while the proportion of sales of atypical antipsychotic drugs always remained high. DDDs increased year by year. For examples, aripiprazole and olanzapine were always the top two in the sales amount and DDDs.The DDC changed greatly, and the DDC of high price varieties, such as olanzapine and amisulpiride, decreased significantly, but the DDC of some low price varieties increased slightly. The B/A of amisulapride, olanzapine and aripiprazole changed greatly, and the B/A of all antipsychotic drugs in 2022 was close to 1.Conclusions The use of antipsychotic drugs in the hospital was rational. The atypical antipsychotic drugs with good curative effect and few adverse effects were mainly used, especially aripiprazole and olanzapine that had the highest frequency of usage. The DDDs of amisulpride and quetiapine increased significantly.

R971

漯河市2022年重大科技创新专项(漯科【2022】45号);2021年度创新创业发展能力提升工程科研类项目(2021LYZKJXM034)