目的 统计青岛市精神卫生中心2019—2021年第二类精神药品使用情况并分析变化趋势，为临床合理用药提供参考。方法 采用回顾性分析方法统计青岛市精神卫生中心信息系统中2019年1月—2021年12月第二类精神药品的销售金额，并计算药品用药频度（DDDs）、限定日费用（DDC）以及药品排序比（B/A）。结果 2019—2021年，医院第二类精神药品销售金额呈逐年增长趋势，奥沙西泮片和佐匹克隆片的销售金额排序始终居于前2位；第二类精神药品的DDDs总体呈增长趋势，佐匹克隆片、氯硝西泮片、阿普唑仑片的DDDs排序始终居于前3位；第二类精神药品的DDC及排序基本稳定，其中奥沙西泮片、地西泮注射液的DDC较高，居于前2位；苯巴比妥片、地西泮片、劳拉西泮片（1 mg）、佐匹克隆片的B/A值接近于1.0。结论 青岛市精神卫生中心第二类精神药品的使用基本合理，后期仍需加强监督管理，以保证患者合理用药。

Objective The use of category II psychotropic drugs in Qingdao Mental Health Center from 2019 to 2021 was analyzed, and the trend was analyzed, providing reference for rational drug use in clinic. Methods The consumption sum of category II psychotropic drugs from January 2019 to December 2021 in the information system of Qingdao Mental Health Center was analyzed retrospectively, and DDDs, DDC and B/A were calculated. Results From 2019 to 2021, the consumption sum of category II psychotropic drugs in hospitals increased year by year, and the consumption sum of Oxazepam Tablets and Zopicalone Tablets always ranked first and second. The DDDs of the second category of psychotropic drugs showed an increasing trend, and the DDDs of Zopiclone Tablets, Clonazepam Tablets, and Alprazolam Tablets always ranked the first 3. The DDC and order of the second type of psychotropic drugs were basically stable, among which the DDC of Oxazepam Tablets and Diazepam Injection were higher, ranking first and second. The B/A values of Phenobarbital Tablets, Diazepam Tablets, Lorazepam Tablets (1 mg) and Zopiclone Tablets were close to 1.0. Conclusion The use of class II psychotropic drugs in Qingdao Mental Health Center was basically reasonable, and supervision and management should be strengthened in the later stage to ensure rational drug use by patients.

R971