目的 通过建立信迪利单抗注射液合理应用评价标准,分析临床用药情况,为合理用药提供参考。方法 参考药品说明书与循证依据制定信迪利单抗注射液临床合理应用评价标准。应用该标准对芜湖市第二人民医院2021年1月至10月使用信迪利单抗注射液患者的病例资料与用药医嘱进行合理性评价。结果 信迪利单抗注射液临床不合理类型主要包括适应证不合理35例(33.98%),特殊要求不符合8例(7.77%)以及用法用量不合理6例(5.83%)。103份病例中,符合说明书适应证1例,超说明书适应证102例(99.03%)。结论 芜湖市第二人民医院建立的信迪利单抗注射液合理使用评价标准有实际应用价值,可为同类药物合理使用提供参考。

Objective To analyze the clinical drug use by establishing the evaluation criteria for rational use of Sintilimab Injection, and to provide reference for rational drug use. Methods The clinical rational application evaluation standard of Sintilimab Injection was formulated with reference to the drug insert and evidence-based basis. This standard was used to evaluate the rationality of the case data and medication orders of patients using Sintilimab Injection in the Second People's Hospital of Wuhu from January to October 2021. Results The clinical unreasonable types of Sintilimab Injection mainly included 35 cases (33.98%) with unreasonable indications, unsuitable special requirements 8 cases (7.77%) and unreasonable usage and dosage 6 cases (5.83%). Among the 103 cases, 1 case met the indications on the label, and 102 cases (99.03%) had off-label indications. Conclusion The evaluation standard for rational use of sintilimab injection established by our hospital has practical application value and can provide a reference for the rational use of similar drugs.

R979.1