目的 分析2019—2020年天津市宝坻区人民医院Ⅰ类切口手术围手术期预防性应用抗菌药物现状，为提高围手术期抗菌药物合理使用提供参考依据。方法 从天津市宝坻区医院信息系统中调取2019年1月1日—2020年12月31日Ⅰ类切口手术出院患者病历10 507例，对围手术期预防用药情况进行分析，每月随机抽样50份病历进行专项点评，总结点评情况。结果 10 507例Ⅰ类切口手术患者中，2 375例预防性使用抗菌药物，抗菌药物预防性使用率为22.60%；使用率最高的科室为骨科（42.04%），使用率最低的科室为泌尿外科（1.24%）；抗菌药物品种选择排名第一的为头孢唑林钠，构成比为86.32%；用药疗程≤24 h的有1 821例（占76.67%），>48 h的有106例（占4.47%）；抽样点评1 200例Ⅰ类切口患者病历，合理用药1 185例（占98.75%），不合理用药15例（占1.25%），主要涉及疗程不适宜（超过24 h且无理由，占比46.67%）、品种不适宜（占比40.00%）。结论 天津市宝坻区人民医院Ⅰ类切口手术围手术期预防性应用抗菌药物的使用基本合理。

Objective To analyze the usage of prophylactic antibiotiscs in perioperative period of type Ⅰ incision in Tianjin Baodi Hospital from January 1, 2019 to December 31, 2020, so as to provide reference for improving the rational use of perioperative antibiotics. Methods A total of 10 507 medical records of discharged patients with type I incision surgery from 2019 to 2020 were collected from the Tianjin Baodi Hospital information system. The preventive medication and rational administration were analyzed. 50 medical records were randomly sampled every month to review and summarize the comments. Results Among 10 507 patients of type Ⅰ incision surgery, 2 375 patients were prophylaxis with antibiotics, and the rate of prophylactic use of antibiotics was 22.60%. The department of orthopedics had the highest utilization rate (42.04%), and the department of urology had the lowest utilization rate (1.24%). The first antibacterial variety was cefazolin sodium, and the composition ratio was 86.32%. There were 1 821 cases (76.67%) whose medication course was less than 24 h, and 106 cases (4.47%) whose medication course was > 48 h. Among 1 200 patients with type I incision, 1 185 cases (98.75%) were used rationally, and 15 cases (1.25%) were used irratively, mainly involving unsuitable course of treatment (more than 24 hours without reason, 46.67%), and unsuitable type (40.00%). Conclusion The prophylactic application of antibiotics in type Ⅰ incision in Tianjin Baodi Hospital is basically rational.

R978.1