目的 分析2018—2020年河南中医药大学第一附属医院中药注射液的应用情况及变化趋势，为临床合理用药提供参考。方法 回顾性分析2018—2020年河南中医药大学第一附属医院中药注射液的销售金额、用药频度（DDDs）、日均费用（DDC）及排序比（B/A）等指标。结果 由于2019年河南省对辅助用药管理的加强，河南中医药大学第一附属医院中药注射液的销售金额出现暂时的下降，之后继续呈现增长趋势，品种数基本保持不变；近3年销售金额排名前5的药品中理血剂占到7个品种，仅1个补益剂是康艾注射液；注射用血栓通和丹红注射液连续3年DDDs排名前2位，而且呈逐年下降趋势；近3年来血必净注射液、心脉隆注射液和瓜蒌皮注射液的DDC值稳居前3，但是其值呈下降趋势；近3年来痰热清注射液和注射用灯盏花素的B/A的值位居前列。结论 河南中医药大学第一附属医院中药注射液的应用以理血剂为主，但还存在一些药品不合理使用的现象，应多方面加强监管，促进临床合理用药。

Objective To analyze utilization and trend of traditional Chinese medicine injections in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from 2018 to 2020, to provide reference for clinical rational use. Methods By a retrospective review, the utilization of traditional Chinese medicine injections in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine from 2018 to 2020 was selected, and consumption sum, DDDs, DDC, and B/A were statistically analyzed. Results Due to the strengthening of auxiliary drugs management in Henan Province in 2019, the consumption sum of traditional Chinese medicine injections in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine temporarily decreased, and then continued to show a growth trend. The number of varieties basically remains invariant. The top 5 drugs in terms of consumption sum were 7 kinds of blood regulating agents for three years. The only tonic medicine was Kangai Injection. Xueshuangtong for Injections and Danhong Injections ranked the top two DDDs over the 3 years. Their DDDs steady declined year by year. The DDC values of Xuebijing Injections, Xinmailong Injection, and Pericarpium Trichosanthis Injections were in the top 3 injections for three years. Their DDC values came down every year. Tanreqing Injections and Breviscapine for injections ranked the top B/A over three years. Conclusion The application of traditional Chinese medicine injections in the First Affiliated Hospital of Henan University of Traditional Chinese Medicine is mainly blood regulating agents, but there are still some unreasonable use of drugs. The strengthening supervision in various aspects is necessary to promote the rational drug use.

R969.3

国家自然科学基金资助项目（81603431）