目的 探讨橘红痰咳液联合复方甲氧那明治疗感染后咳嗽的临床效果。方法 选择2018年1月-2020年12月天津中医药大学第一附属医院急诊科收治的140例感染后咳嗽患者为研究对象，根据用药差别分为对照组（67例）和治疗组（73例），对照组口服复方甲氧那明胶囊，2粒/次，3次/d。治疗组在对照组的基础上口服橘红痰咳液，20 mL/次，3次/d。两组疗程最长为7 d。观察两组患者临床疗效，比较治疗前后两组患者视觉模拟咳嗽症状积分（VAS评分）、莱切斯特咳嗽问卷中文版（LCQ-MC）评分和止咳时间。结果 经治疗，对照组愈显率为65.67%，显著低于治疗组的82.19%（P<0.05）。治疗后，两组VAS评分明显降低，而LCQ-MC各维度评分明显升高（P<0.05），且治疗组患者VAS和LCQ-MC评分显著好于对照组（P<0.05）。治疗后，治疗组咳嗽缓解时间及咳嗽停止时间均显著短于对照组（P<0.05）。结论 橘红痰咳液联合复方甲氧那明治疗感染后咳嗽效果良好，可进一步改善临床症状，缩短咳嗽病程，具有一定临床推广应用价值。

Objective To investigate the clinical effect of Juhong Tanke Liquid combined with compound methoxyphenamine in treatment of post-infectious cough. Methods Patients (140 cases) with post-infectious cough in the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine from January 2018 to December 2020 were divided into control (67 cases) and treatment (73 cases) groups based on different treatments. Patients in the control group were po administered with Compound Methoxyphenamine Hydrochloride Capsules, 2 grains/time, three times daily. Patients in the treatment group were po administered with Juhong Tanke Liquid, 20 mL/time, three times daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, the improvement time of clinical symptoms, the scores of VAS and LCQ-MC, and cough relief time in two groups before and after treatment were compared. Results After treatment, the cured and markedly effective rate in the control group was 65.67%, which was significantly lower than 82.19% in the treatment group (P<0.05). After treatment, the scores of VAS in two groups were significantly decreased, while the scores of LCQ-MC were significantly increased (P<0.05), and the scores of VAS and LCQ-MC in the treatment group were significantly better than those in the control group (P<0.05). After treatment, the cough relief time and cough stop time in the treatment group were significantly less than those in the control group (P<0.05). Conclusion The effect of Juhong Tanke Liquid combined with compound methoxyphenamine in treatment of post-infectious cough is good, can further improve the clinical symptoms and shorten the course of cough, which has a certain clinical application value.

R974

天津中医药大学第一附属医院“拓新工程”科研课题（201909）