目的 探讨喜炎平注射液联合头孢西丁治疗急性扁桃体炎的临床疗效。方法 选取柞水县中医医院内科门诊2019年10月—2020年7月收治的60例急性扁桃体炎患者，采用照随机数字表法分为对照组和治疗组，每组各30例。对照组静脉滴注注射用头孢西丁钠，4 g溶于250 mL生理盐水，1次/d。治疗组在对照组治疗基础上静脉滴注喜炎平注射液，10 mL溶于5%葡萄糖溶液100 mL中，1次/d。两组均连续治疗2～5 d。观察两组的临床疗效，比较两组临床症状缓解时间、感染性相关指标。结果 治疗后，治疗组总有效率是96.7%，显著高于对照组的83.3%（P<0.05）。治疗后，治疗组咽痛、发热恶寒、头痛头晕、鼻塞流涕等临床症状改善时间明显短于对照组（P<0.05）。治疗后，两组患者白细胞计数（WBC）、中性粒细胞、高敏C反应蛋白（hs-CRP）均较治疗前显著降低（P<0.05）；且治疗后治疗组炎症指标显著低于对照组（P<0.05）。结论 喜炎平注射液联合头孢西丁治疗急性扁桃体炎具有较好的临床疗效，可以显著缩短患者临床症状缓解时间，降低感染性相关指标，具有一定的临床推广应用价值。

Objective To investigate the clinical efficacy of Xiyanping Injection combined with cefoxitin in treatment of acute tonsillitis. Methods A total of 60 patients with acute tonsillitis admitted to the internal medicine department of Zhashui County Hospital of Traditional Chinese Medicine from October 2019 to July 2020 were selected and divided into control group and treatment group by random number table method, with 30 patients in each group. Patients in the control group were iv administered with Cefoxitin Sodium for injection, 4 g was dissolved in 250 mL normal saline, once daily. Patients in the treatment group were iv administered with Xiyanping Injection on the basis of the control group, 10 mL was dissolved in 100 mL 5% glucose solution, once daily. Both groups were treated continuously for 2 — 5 d. The clinical efficacy of the two groups was observed, and the clinical symptom remission time and related indexes of infection were compared between the two groups. Results After treatment, the total effective rate of the treatment group was 96.7%, which was significantly higher than that of the control group (83.3%, P < 0.05). After treatment, the improvement time of clinical symptoms such as sore throat, fever and cold, headache and dizziness, nasal congestion, and runny nose in the treatment group was significantly shorter than that in the control group (P < 0.05). After treatment, the white blood cell count (WBC), neutrophils, and high-sensitivity C-reactive protein (hs-CRP) in two groups were significantly decreased compared with before treatment (P < 0.05). After treatment, inflammatory indexes in the treatment group were significantly lower than those in the control group (P < 0.05). Conclusion Xiyanping Injection combined with cefoxitin has a good clinical effect in treatment of acute tonsillitis, and can significantly shorten the time of clinical symptom remission, reduce the relevant indicators of infection, which has a certain value of clinical promotion and application.

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南京市中医药青年人才培养计划项目（ZYQ20065）