目的 分析2015—2019年天津市眼科医院局部抗青光眼药品的使用情况及发展趋势。方法 对天津市眼科医院2015—2019年局部抗青光眼药品的销售金额、用药频度（DDDs）、日均费用（DDC）、排序比（B/A）等进行回顾性统计分析。结果 前列腺素衍生物类局部抗青光眼药品的销售金额远高于其他4类药品销售金额。拉坦前列素滴眼液（国产）、拉坦前列素滴眼液（进口）、曲伏前列素滴眼液、盐酸卡替洛尔滴眼液、酒石酸溴莫尼定滴眼液、布林佐胺滴眼液稳居本院用药金额前6位。盐酸卡替洛尔滴眼液DDD稳居第1位。除了2015—2016年盐酸卡替洛尔滴眼液的DDC值略有上升外，其他滴眼液的DDC值均维持不变或呈下降的趋势。盐酸卡替洛尔滴眼液的B/A最高。结论 本院局部抗青光眼药品使用基本合理，前列腺素衍生物类药物逐渐成为抗青光眼的一线用药。

Objective To analyze the use and development trend of local anti-glaucoma drugs in Tianjin Eye Hospital from 2015 to 2019. Methods The sales amount, drug frequency (DDDs), average daily cost (DDC), and ranking ratio (B/A) of local anti-glaucoma drugs in Tianjin Eye Hospital from 2015 to 2019 were statistically analyzed. Results The sales amount of prostaglandin local anti-glaucoma drugs was much higher than that of other four drugs. Ratanprost eye drops (domestic), ratanprost eye drops (imported), triprost eye drops, cateolol hydrochloride eye drops, bromomonidine tartrate eye drops, and brinzolamine eye drops were in the top 6 of sales amount. DDD of catarrhalol hydrochloride eye drops ranked first. Except for the DDC value of catarral hydrochloride eye drops increased slightly from 2015 to 2016, the DDC value of other eye drops remained unchanged or showed a downward trend. Catarrhhalol hydrochloride eye drops had the highest B/A. Conclusion The use of local anti-glaucoma drugs in Tianjin Eye Hospital is reasonable, and prostaglandin derivatives have gradually become the first-line anti glaucoma drugs.

R988.1