目的 分析天津中医药大学第一附属医院胰岛素类药物的使用情况和变化趋势，为促进临床合理用药提供参考。方法 通过医院信息系统（HIS）提取2017-2019年天津中医药大学第一附属医院胰岛素类药物的销售金额、使用频度（DDDs）、日均费用（DDC）和排序比（B/A）等进行统计和分析。结果 2017-2019年共有11种胰岛素类药物供临床使用，销售金额和构成比呈先下降后上升的趋势。甘精胰岛素注射液的销售金额及构成比连续3年居第1位，门冬胰岛素30注射液次之。胰岛素类各品种的金额和DDDs排序无显著波动，排名基本稳定，只有地特胰岛素的上升幅度较大。除胰岛素注射液和地特胰岛素注射液外，其余品种的DDC值均逐年小幅下降。除门冬胰岛素30注射液外，其余品种的B/A比值均接近1.00。结论 天津中医药大学第一附属医院胰岛素类药物的选择和使用基本合理，个别增长速度过快品种需密切关注，确保临床用药规范合理。

Objective To analyze the utilization and tendency of insulin drugs in First Teaching Hospital of Tianjin University of TCM, and in order to provide reference and management for clinical rational use of drugs. Methods The relevant data of utilization of insulin drugs in First Teaching Hospital of Tianjin University of TCM from 2017 to 2019 was selected from Hospital Information Systems (HIS), and drug varieties, sales amount, defined daily doses (DDDs), defined daily cost (DDC), and sorting ratio (B/A) were analyzed statistically. Results From 2017 to 2019, there were 11 insulin kinds for clinical use, and the sales amount and composition ratio showed a downward trend first and then upward trend. The sales amount and composition ratio of Insulin Glargine Injection ranked the first for three consecutive years, followed by insulin Aspart 30 Injection. There was no significant fluctuation in the amount and DDDs of insulin varieties. The ranking was basically stable, but the rising range of Insulin Detemir Injection was large. In addition to Insulin Injection and Insulin Detemir Injection, DDC of other varieties decreased slightly year by year. The B/A of the other varieties was close to 1.00 except for Insulin Aspart 30 Injection.Conclusion The selection and use of insulin drugs in the First Teaching Hospital of Tianjin University of TCM are basically reasonable, and the individual varieties with excessive growth rate need to be paid more attention to ensure that the use of drugs is standardized and reasonable.

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