目的 对漯河市中心医院西城分院第二类精神药品的用药情况进行调查分析，为临床合理用药提供参考。方法 收集2017-2019年漯河市中心医院西城分院第二类精神药品的用药数据，将其用量、销售金额、用药频度（DDDs）、日均费用（DDC）及排序比（B/A）等指标进行统计和分析。结果 第二类精神药品以苯二氮（艹卓）类为主，其销售金额呈逐年增长趋势，其中劳拉西泮片的DDDs最大，连续3年均居第1位，奥沙西泮片和唑吡坦片的销售金额、DDDs增长幅度最大；奥沙西泮片和右佐匹克隆片的DDC排名较高，3年内均居前2位；奥沙西泮片的B/A最小，阿普唑仑片和劳拉西泮片的B/A均比较大。结论 漯河市中心医院西城分院第二类精神药品的临床使用基本合理，个别品种使用率较高，提示临床需加强管理，避免滥用产生依赖。

Objective To investigate and analyze the application of type Ⅱ psychotropic drugs in Xicheng Branch of Luohe Central Hospital, so as to provide references for clinical reasonable application. Methods The utilization date of type Ⅱ psychotropic drugs in Xicheng Branch of Luohe Central Hospital from 2017 to 2019 was collected, and the sales amount, sales sum, frequency of drug use (DDDs), daily average cost (DDC) and sequence ratio (B/A) of type Ⅱ psychotropic drugs were analyzed. Results Benzodiazepines were the main type Ⅱ psychotropic drugs. The sales sum of type Ⅱ psychotropic drugs were increased year by year. Lorazepam Tablets had the largest DDDs ranking the first for three consecutive years. DDDs of Oxazepam Tablets and Zolpidem Tablets were increased significantly. DDC of Oxazepam Tablets and Eszopiclone Tablets ranked the top two in the three years. Oxazepam Tablets had the lowest sequence ratio and Alprazolam Tablets and Lorazepam Tablets had larger sequence ratio than others. Conclusion The use of the type Ⅱ psychotropic drugs is basically reasonable in Xicheng Branch of Luohe Central Hospital, but the use rate of individual varieties is high, which suggests that the management should be strengthened in order to avoid the drug dependence caused by long term abuse of such drugs.

R971

河南省工程研究中心资助项目（豫发改高技[2019]569号）；漯河市工程技术研究中心资助项目（漯科[2018]88号）；漯河市创新型科技团队资助项目（漯科[2018]88号）