目的 了解天津市津南医院麻醉药品的使用情况和变化趋势，为促进临床合理应用麻醉药品提供依据。方法 对2017-2019年天津市津南医院麻醉药品的使用数量、销售金额、用药频度（DDDs）、日均用药费用（DDC）及药品排序比（B/A）等进行统计和分析。结果 2017-2019年麻醉药品的销售总金额逐年递增，构成比浮动较大。枸橼酸舒芬太尼注射液和注射用盐酸瑞芬太尼销售金额的排名平稳，始终居前两位。盐酸吗啡缓释片的DDDs排名先下降后上升，2019年跃居首位。有9种麻醉药品的DDC都在50元以下。麻醉药品的B/A比值基本上均接近于1，说明各类麻醉药品的用药同步性良好。结论 天津市津南医院麻醉药品应用基本合理，但仍存在一些不足，还需进一步加强麻醉药品管理。

Objective To understand the use and change trend of narcotic drugs in Tianjin Jinnan Hospital, and to provide a basis for promoting the rational use of narcotic drugs in the clinic. Methods The sales volume, sales amount, frequency of drug use (DDDs), daily average drug cost (DDC), and drug ranking ratio (B/A) of narcotic drugs in Tianjin Jinnan Hospital from 2017 to 2019 were statistically analyzed. Results From 2017 to 2019, the total sales amount of narcotic drugs increased year by year, and the composition ratio remained basically larger than the float. The ranking of sales amount of Sufentanil Citrate Injection and Remifentanil Hydrochloride for Injection ranked stable, always ranking the top two. The ranking of DDDs of Morphine Hydrochloride Sustained-release Tablets first decreased and then increased, and it jumped to the top in 2019. There were 9 kinds of narcotic drugs whose DDC was below 50 yuan. The B/A ratio of various narcotic drugs was basically close to 1, indicating that the synchronization of various narcotic drugs was good. Conclusion The application of narcotic drugs in Tianjin Jinnan Hospital is basically reasonable, but there are still some shortcomings, and the management of anesthetic drugs needs to be further strengthened.

R971

国家自然科学基金青年基金资助项目（81803524）