目的 分析南京地区60家医院2016-2018年神经系统辅助用药的使用情况，评价该类药物在临床的使用现状与趋势。方法 收集2016-2018年南京地区60家医院神经系统辅助用药的使用数据，对用药金额、用药频度（DDDs）、日均费用（DDC）和药品排序比（B/A）进行统计分析。结果 2016-2018年南京地区60家医院神经系统辅助用药的总销售金额呈下降趋势，改善脑代谢类药物和改善脑循环类药物在神经系统辅助用药内占主导地位。销售金额前3位的药物分别为奥拉西坦、单唾液酸四己糖神经节苷脂钠和前列地尔，总体呈下降趋势。DDDs总量呈上升趋势，其中排名前3位的药物有胞磷胆碱、血塞通和前列地尔。DDC排名前3位的药物为依达拉奉、单唾液酸四己糖神经节苷脂钠和鼠神经生长因子。0.5 ≤ B/A ≤ 1.5的品种有18、17、16种；DDC排名前3的药物为依达拉奉、单唾液酸四己糖神经节苷脂钠和鼠神经生长因子。结论 南京地区60家医院神经系统辅助用药的使用基本合理，且各类药物的使用基本呈下降趋势。

Objective To analyze the utilization of nervous system auxiliary drugs in 60 hospitals in Nanjing area from 2016 to 2018, and in order to evaluate the status quo and trends of nervous system auxiliary drugs. Methods The data of nervous system auxiliary drugs in 60 hospitals from Nanjing area from 2016 to 2018 were collected, and consumption sum, defined daily doses (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were analyzed statistically. Results From 2016 to 2018, the total sales of nervous system auxiliary drugs in 60 hospitals in Nanjing area were on a declining curve. Drugs that improve brain metabolism and improve brain circulation were dominated in nervous system auxiliary drugs. Consumption sum of oxiracetam, tetrahexosaccharide monosalic acid ganglioside sodium, and alprostadil were ranked for the top three. The overall trend was downward. DDDs had the trend of increase, in which DDDs of citicoline, xuesetong, and alprodil were ranked for the top three. There were 18, 17, and 16 species of drugs with B/A between 0.5 and 1.5. DDC of edaravone, tetrahexyl monosialic acid ganglioside sodium, and rat nerve growth factor were ranked for the top three. Conclusion The use of nervous system auxiliary drugs in 60 hospitals in Nanjing area from 2016 to 2018 is basically reasonable, and the use of various drugs show a decreasing trend.

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