目的 对2017-2018年吉林大学第一医院风湿科骨瓜提取物注射液的住院处方进行专项点评，为临床提供参考依据。方法 通过吉林大学第一医院HIS系统提取2017年1月-2018年12月风湿科骨瓜提取物注射液住院处方，根据药品说明书对其进行点评，点评内容包括适应症、溶媒选择和用量、给药频次及疗程等，并对所点评的结果进行归纳、统计、分析。结果 骨瓜提取物注射液的超浓度用药患者主要集中在18~59、60~69岁，构成比分别为27.17%、24.15%。适应症主要为类风湿性关节炎（1 106例），构成比为51.83%。溶媒选择0.9%氯化钠注射液或5%葡萄糖注射液100或250 mL。其中超溶媒剂量使用的占总处方数的12.41%。使用频次均为1次/d，疗程最长为15 d。结论 吉林大学第一医院风湿科骨瓜提取物注射液的临床使用情况良好，应在老年人用药的特殊性方面需要提高关注度，以确保患者用药的安全性。也希望生产厂家及时更新药品说明书，保障用药的安全性。

Objective To evaluate the rationality of Gugua Extractives Injection in hospital prescription for special comment in Department of Rheumatology of the First Hospital of Jilin University from 2017 to 2018, and to provide reference for clinical practice. Methods The inpatient prescription of Gugua Extractives Injection in Department of Rheumatology of the First Hospital of Jilin University from January 2017 to December 2018 was extracted by HIS system. The contents of the commons included indication, solvent selection and dosage, frequency, and course of treatment, etc. according to the instructions, and the review results were summarized, counted and analyzed. Results Most patients with superconcentration of Gugua Extractives Injection were 18-59 and 60-69 years old, accounting for 27.17% and 24.15%. The indications was mainly rheumatoid arthritis (1 106 cases), accounting for 51.83%. The choice of solvent was 0.9% sodium chloride injection or 5% glucose injection with 100 or 250 mL. The hypersolvent dose accounted for 12.41% in total number of prescriptions. The frequency of usage was once per day. The maximum duration of treatment was 15 d. Conclusion The clinical use of Gugua Extractives Injection in Department of Rheumatology of the First Hospital of Jilin University is in good condition. It should be need to raise awareness in the particularity of the elderly medication, in order to ensure the safety of medication for patients. It is also hoped that manufacturers can update the drug instructions in time to ensure the safety of medication.

R969.3