目的 分析天津市宝坻区人民医院住院患者特殊使用级抗菌药物的使用情况，为临床合理应用特殊使用级抗菌药物提供参考依据。方法 从医院信息系统调取天津市宝坻区人民医院2018年1~12月使用特殊使用级抗菌药物出院患者的基本信息，分析患者性别、年龄、用药频次、销售金额及构成比、用药总量、用药频度（DDDs）等情况。结果 特殊使用级抗菌药物应用年龄较多的前两个年龄段为60~74、75~89岁；使用频次最高的为美罗培南（915例），构成比为68.39%；2018年特殊使用级抗菌药物的销售金额为430.78万元，构成比为41.87%；特殊使用级抗菌药物中美罗培南的使用频率、销售金额、总消耗量、DDDs及排序均为首位。结论 2018年天津市宝坻区人民医院特殊使用级抗菌药物的使用基本合理，但仍需要进一步加强管理。

Objective To analyze the application of special class antibiotic drugs in inpatients of Tianjin Baodi Hospital in 2018, in order to provide reference for rational use of special class antibiotic drugs in clinic. Methods The application data of the special class antimicrobial drugs in inpatients of the Tianjin Baodi Hospital in 2018 was extracted from the hospital information system (HIS). The gender, age, frequency of drug use, consumption sums and constituent ratio, total amounts, and DDDs were recorded and analyzed. Results The first two segments for using special class antibiotic drugs were 60-74 years old and 75-89 years old. Meropenem had the most frequency of usage (915 cases), accounting for 68.39%. In 2018, the total amount of special class antibiotic drugs was 4.307 8 million yuan, accounting for 41.87%. Sales amount, total dosage, DDD, and DDDs of meropenem in special class antibiotic drugs were ranked the first. Conclusion The application of special class antibiotic drugs in inpatients of Tianjin Baodi Hospital in 2018 is basically reasonable, however, further management needs to be strengthened.

R978.1