目的 分析2016-2018年河南省洛阳正骨医院活血化瘀类中药注射剂的临床使用现状，为临床合理用药提供参考。方法 随机选取2016-2018年河南省洛阳正骨医院骨科手术患者360例，其中使用丹红注射液、疏血通注射液、注射用血塞通、红花注射液、注射用血栓通、灯盏细辛注射液各60例，对其指征用药、给药时间、联合用药、溶剂选择、给药剂量与疗程等情况进行分析。结果 无指征用药79例，占21.94%，其中注射用血塞通和灯盏细辛注射液的无指征用药例数较多，构成比分别为35.00%、36.67%。给药时间差异较大，术后24 h以内活血化瘀类中药注射剂的使用例数最多，构成比为48.89%。联合用药81例，占22.5%；注射用血塞通、灯盏细辛注射液溶剂选择的错误率较高，分别为70.00%、66.67%；超剂量给药7例，占1.94%。结论 河南省洛阳正骨医院活血化瘀类中药注射剂的使用基本合理，但也存在一定的问题，应规范该类中药注射剂的临床应用，确保患者安全用药。

Objective To analyze the clinical use of traditional Chinese medicine (TCM) injections for promoting blood circulation and removing blood stasis in Luoyang Orthopedic-Traumatological Hospital of Henan Province from 2016 to 2018, and to provide reference for clinical rational drug use. Methods A total of 360 patients with orthopedic surgery in Luoyang Orthopedic-Traumatological Hospital of Henan Province from 2016 to 2018 were randomly selected, including Danhong Injection, Honghua Injection, Shuxuetong Injection, Xuesaitong for injection, Xueshutong for injection, and Dengzhanxixin Injection, and each had 60 cases. Indications, time of administration, combination of drugs, choice of solvent, dose and course of treatment, and adverse reactions were analyzed. Results There were 79 cases without indications, accounting for 21.94%. In which, Xuesaitong for injection and Dengzhanxixin Injection had the more cases without indications, accounting for 35.00% and 36.67%. There were significant differences between administration times. The most TCM injections used to promote blood circulation and remove stasis were within 24 h after the operation, accounting for 48.89%. There were 81 cases combined, accounting for 22.5%. Xuesaitong for injection and Dengzhanxixin Injection had the more error rate in solvent selection, accounting for 70.00% and 66.67%. There were 7 cases were over-dosed, accounting for 1.94%. Conclusion The use of traditional Chinese medicine (TCM) injections for promoting blood circulation and removing blood stasis is basically reasonable, but there are also certain problems. The clinical application of traditional Chinese medicine injection should be standardized to ensure the safe use of drugs by patients.

R969.3

河南省中医药科学研究专项课题（2017ZY2089）；河南省中医药拔尖人才项目（豫中医科教[2018]35号）