目的 对2017-2018年江苏省中医院脑梗死住院患者使用活血化瘀类中药注射剂的合理性进行分析，促进合理使用。方法 采用回顾性分析的方法对江苏省中医院800例脑梗死的病历进行分析，调查活血化瘀类中药注射剂的使用种类、适应症、用药时机、用药疗程、用法用量、溶媒的选择及溶媒量、联合用药情况以及使用时是否发生不良反应，通过分析找出其使用不合理的地方，并提出相应的整改措施。结果 共有11种活血化瘀类中药注射剂用于脑梗死患者的辅助治疗。使用率最高的活血化瘀类中药注射剂为银杏二萜内酯葡胺注射液，使用率达34.68%。316例患者存在超适应症用药，占39.50%。超疗程使用占总使用频次的1.91%。未按说明书推荐使用的稀释溶媒有2.50%。联合使用的治疗脑梗死的相关药物有17种。结论 江苏省中医院脑梗死住院患者的在活血化瘀类中药注射剂的使用上存在一定的不合理用药现象，需加强对活血化瘀类中药注射剂在使用中的监测和管理。

Objective To evaluate the rationality of traditional Chinese medicine injections for promoting blood circulation in patients with cerebral infarction in Jiangsu Province Hospital of Chinese Medicine from 2017 to 2018, to promote the use of traditional Chinese medicine injections for promoting blood circulation in patients with cerebral infarction. Methods A retrospective analysis method was used to analyze the 800 cases of cerebral infarction in Jiangsu Province Hospital of Chinese Medicine. The types of traditional Chinese medicine injections, indications, timing of medication, course of medication, usage and dosage, choice of solvent and amount of solvent, combination of drugs, and adverse drug reactions were evaluated to find out the unreasonable places and proposing corresponding corrective measures. Results There were 11 kinds of traditional Chinese medicine injections for the treatment of cerebral infarction. The highest utilization rate of Chinese medicine injection was Ginkgo Biloba Lactone Glucamine Injection with the utilization rate of 34.68%. There were 316 cases of super-instruction medication, accounting for 39.50%. The frequency of use of the super-treatment was 1.91%. The diluted solvent which was not recommended according to the instructions was 2.50%. There were 17 kinds of combined antithrombotic drugs. Conclusion There are some unreasonable drug use phenomenon of traditional Chinese medicine injections for promoting blood circulation in patients with cerebral infarction in Jiangsu Province Hospital of Chinese Medicine, and it is necessary to strengthen the monitoring and administration of clinical use of Chinese medicine injections.

R971

江苏省药学会-天晴医院药学基金资助项目（Q2018011）