目的 探讨白带净胶囊联合奥硝唑阴道栓治疗滴虫性阴道炎的临床疗效。方法 选取2018年1月-2019年1月在中国人民解放军河南总队医院治疗的80例滴虫性阴道炎患者，根据用药的差别分为对照组（40例）和治疗组（40例）。对照组给予奥硝唑阴道栓，每晚睡前一次，洗净阴道后给予1枚置于阴道深处；治疗组在对照组基础上给予白带净胶囊，一次1粒，3天1次，置于阴道深处。两组均经7 d治疗。观察两组的临床疗效，比较两组治疗前后相关评分、血清学指标的变化情况。结果 治疗后，对照组和治疗组的总有效率分别是80.0%、97.5%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组外阴瘙痒、阴道分泌物、外阴灼痛、阴道黏膜充血等症状评分均较治疗前显著下降，同组治疗前后比较差异有统计学意义（P<0.05）；治疗后，治疗组这些临床症状积分显著低于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组阴道健康评分、GQOL-74评分均显著升高，而SAS评分显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；治疗后，治疗组阴道健康评分、GQOL-74评分显著高于对照组，而SAS评分显著低于对照组，两组比较差异具有统计学意义（P<0.05）。两组血清白细胞介素-8（IL-8）、肿瘤坏死因子-α（TNF-α）、单核细胞超化蛋白-1（MCP-1）、转化生长因子-β1（TGF-β1）水平均较治疗前显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；治疗后，治疗组这些血清学指标均显著低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 白带净胶囊联合奥硝唑阴道栓治疗滴虫性阴道炎具有较好的临床疗效，可有效改善患者临床症状，改善患者阴道健康情况及焦虑状态，促进患者生活质量提高，降低机体炎症反应，有一定的临床推广应用价值。

Objective To explore the clinical efficacy of Baidaijing Capsules combined with Ornidazole Vaginal Suppositories in treatment of trichomonal vaginitis. Methods Patients (80 cases) with trichomonal vaginitis in Henan General Hospital of the People's Liberation Army of China from January 2018 to January 2019 were divided into control (40 cases) and treatment (40 cases) groups according to different medication regimens. Patients in the control group were given Ornidazole Vaginal Suppositories, once every night before going to bed, patients were given a Ornidazole Vaginal Suppositories into deep vagina after washing the vagina. Patients in the treatment group were given Baidaijing Capsules deep into the vagina on the basis of the control group, 1 capsule/time, once every 3 days, Patients in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, and the changes of related scores and serological indicators in two groups were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 80.0% and 97.5%, respectively, and there were differences between two groups (P<0.05). After treatment, the scores of vulva itch, vaginal discharge, vulva burning pain, and vaginal mucosal congestion in the two groups were significantly lower than those before treatment, and there were differences in the same group (P<0.05). After treatment, those clinical symptom scores were significantly lower in the treatment group than in the control group, and there were differences between two groups (P<0.05). After treatment, vaginal health scores and GQOL-74 scores were significantly increased in both groups, but SAS scores were significantly decreased, and there were differences in the same group (P<0.05). After treatment, the vaginal health score and GQOL-74 score of the treatment group were significantly higher than those of the control group, but the SAS score was significantly lower than that of the control group, and there were differences between two groups (P<0.05). After treatment, IL-8, TNF-α, MCP-1, and TGF-β1 in the two groups were significantly lower than those before treatment, and there were differences in the same group (P<0.05). After treatment, those serological indicators were significantly lower in the treatment group than in the control group, and there were differences between two groups (P<0.05). Conclusion Baidaijing Capsules combined with Ornidazole Vaginal Suppositories has significant effect in treatment of trichomonal vaginitis, and can effectively improve the clinical symptoms of the patients, improve the vaginal health and anxiety of the patients, and also can promote the improvement life quality, and reduce the inflammatory response of the body, which has a certain clinical application value.