[关键词]
[摘要]
目的 调查常州市第一人民医院住院患者质子泵抑制剂的使用情况,并进行合理性分析,为临床合理用药提供参考。方法 抽取常州市第一人民医院2018年住院患者质子泵抑制剂的相关使用数据进行统计分析,并每月随机抽取50份病例,共600份,进行用药合理性分析。结果 住院患者中销售金额和用药频度均排名前列的有注射用奥美拉唑和注射用泮托拉唑。600份病例中,不合理病历406份,占67.67%,主要问题有无适应症用药(45.00%)、给药途径不当(22.14%)、用法用量不适宜(26.31%)、疗程不适宜(4.36%)、重复用药(2.00%)和联合用药不当(0.18%)。结论 常州市第一人民医院质子泵抑制剂临床使用存在较多不合理现象,需加强监管和干预,提升合理用药水平。
[Key word]
[Abstract]
Objective To investigate the application and its rationality of proton pump inhibitors (PPIs) of inpatients in the First People's Hospital of Changzhou, so as to provide references for clinical rational medication. Methods Clinical data of the utilization of PPIs of inpatients in the First People's Hospital of Changzhou in 2018 were collected and analyzed statistically. In addition, 50 cases were randomly selected per month, a total of 600 cases, to evaluate the rationality of drug use. Results Omeprazole for injection and Pantoprazole for injection were the top two at DDDs and amount of money among inpatients. In 600 pieces of medical history, 406 pieces were in irrational application of PPIs, accounted for 67.67%. The main problem of the irrational use of PPIs consisted of unclear indications of medication (45.00%), improper selections of administration routes (22.14%), inappropriate usage and dosage (26.31%), inappropriate treatment courses (4.36%), repeated drug use (2.00%) as well as improper combination (0.18%). Conclusion There are some unreasonable uses of PPIs in the First People's Hospital of Changzhou, and supervision and intervention should be strengthened to elevate the level of rational drug use.
[中图分类号]
R969.3;R975
[基金项目]