目的 对天津市蓟州区人民医院注射用红花黄色素的使用现状进行研究及合理性分析，为临床合理用药提供参考。方法 抽取天津市蓟州区人民医院2018年应用注射用红花黄色素的出院病历1 169份，抽样点评其中880份，根据注射用红花黄色素说明书及循证医学依据，对注射用红花黄色素临床应用的合理性进行统计分析。结果 使用注射用红花黄色素的科室主要为心内科、神经内科、老年科和骨科，构成比分别为83.13%、14.54%、1.16%、0.86%。用药原因主要为心血管疾病（59.32%）、脑血管疾病（20.00%）。注射用红花黄色素的不合理使用率为36.82%，其中溶媒选择不合理例数最多，为157例（49.09%），其次为疗程不合理115例（13.07%），给药剂量不合理27例（3.07%）、配伍不合理14例（1.59%）、适应症不适宜11例（1.25%）。结论 2018年天津市蓟州区人民医院注射用红花黄色素的临床应用存在一定不合理现象，建议加强医师合理用药知识培训，提高药师审核医嘱能力，规范中药注射剂的管理与应用，保障患者用药安全。

Objective To study and analyze the current situation of the application of Safflower Yellow for injection in the People's Hospital of Jizhou District, Tianjin, and to provide reference for clinical rational drug use. Methods A total of 1 169 discharge medical records of Safflower Yellow for injection were selected from the People's Hospital of Jizhou District, Tianjin in 2018, among which 880 cases were sampled and reviewed. The rationality of clinical application of Safflower Yellow for injection was statistically analyzed based on the instructions of Safflower Yellow for injection and evidence-based medicine. Results The departments using Safflower Yellow for injection were mainly Department of Cardiology, Department of Neurology, Department of Geriatric, and Department of Orthopedics, with composition ratio of 83.13%, 14.54%, 1.16%, and 0.86%, respectively. The main causes were cardiovascular disease (59.32%) and cerebrovascular disease (20.00%). The unreasonable utilization rate of Safflower Yellow for injection was 36.82%. Among them, unreasonable solvent selection was the most with 157 cases (49.09%), followed by unreasonable course of treatment with 115 cases (13.07%), unreasonable dosage with 27 cases (3.07%), unreasonable compatibility with 14 cases (1.59%), and inappropriate indications with 11 cases (1.25%). Conclusion There are some unreasonable phenomena in the clinical application of Safflower Yellow for injection in the People's Hospital of Jizhou District, Tianjin in 2018. It is suggested to strengthen the knowledge training of rational drug use by physicians, improve the ability of pharmacists to review doctor's advice, standardize the management, and application of traditional Chinese medicine injection, and ensure the medication safety of patients.

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