目的 分析天津市津南区咸水沽医院抗高血压药物的应用情况和趋势，为临床合理用药提供参考。方法 对2015—2017年天津市津南区咸水沽医院抗高血压药物的应用品种、销售金额、用药频度（DDDs）及日均药费（DDC）进行统计和分析。结果 2015—2017年抗高血压药物的销售金额呈逐年上升的趋势，构成比相对稳定。销售金额和DDDs排名前10位的抗高血压药物主要是钙通道阻滞剂（CCB）、血管紧张素Ⅱ受体拮抗剂（ARB）这两类药物。左旋氨氯地平、硝苯地平、美托洛尔在2015—2017年中均位居销售金额前4位。硝苯地平在2015—2017年均位居DDDs首位。2015—2017年DDC排名前10位的抗高血压药物中，除了硝普钠的DDC大于10元，其他类全部低于10元，且大部分的DDC值均在3元左右。结论 天津市津南区咸水沽医院抗高血压药物以CCB、ARB和β-受体阻滞剂（β-RB）为主，使用基本合理。

Objective To analyze the usage and trend of antihypertensive drugs in Jinnan Xianshuigu Hospital of Tianjin City, and to provide a reference for clinical rational drug use. Methods Statistics and analysis were conducted on the types, sales amount, frequency of use (DDDs), and daily average cost (DDC) of antihypertensive drugs in Jinnan Xianshuigu Hospital of Tianjin City from 2015 to 2017. Results The sales amount of antihypertensive drugs from 2015 to 2017 showed an increasing trend year by year, and the composition ratio was relatively stable. Antihypertensive drugs with top 10 sales amount and DDDs were calcium channel blockers (CCB) and angiotensin Ⅱ receptor antagonist (ARB). Sales amount of levamlodipine, nifedipine, and metoprolol from 2015 to 2017 ranked the top four. DDDs of nifedipine from 2015 to 2017 ranked the first. In the antihypertensive drugs with top 10 DDC from 2015 to 2017, DDC of sodium nitroprusside was more than 10 yuan, while DDC of others was lower than 10 yuan. And DDC of most antihypertensive drugs were near to 3 yuan. Conclusion The antihypertensive drugs in Jinnan Xianshuigu Hospital of Tianjin City are mainly CCB, ARB, and β-RB, and their use is reasonable.