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[摘要]
目的 探讨肿痛安胶囊联合西地碘含片治疗牙龈炎的临床疗效。方法 选取2015年6月-2017年6月天津市第三中心医院分院收治的牙龈炎患者120例为研究对象,将所有患者随机分为对照组和治疗组,每组各60例。对照组口服西地碘含片,1片/次,3次/d。治疗组在对照组治疗的基础上口服肿痛安胶囊,2粒/次,3次/d。两组患者均连续使用10 d。观察两组的临床疗效,比较两组的牙周指标牙龈指数(GI)评分、菌斑指数(PLI)评分、牙龈探诊出血(BOP)。结果 治疗后,对照组和治疗组的总有效率分别为80.00%、95.00%,两组比较差异有统计学意义(P<0.05)。治疗后,两组GI评分、BOP和PLI评分均显著降低,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组牙周指标明显低于对照组,两组比较差异具有统计学意义(P<0.05)。结论 肿痛安胶囊联合西地碘含片治疗牙龈炎具有较好的临床疗效,可改善患者牙周指标,安全性较好,具有一定的临床推广应用价值。
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[Abstract]
Objective To investigate the clincal effect of Zhongtong'an Capsules combined with Cydiodine Buccal Tablets in treatment of gingivitis. Methods Patients (120 cases) with gingivitis in the Branch of Tianjin Third Central Hospital from June 2015 to June 2017 were randomly divided into control and treatment groups, and each group had 60 cases. Patients in the control group were po administered with Cydiodine Buccal Tablets, 1 tablet/time, three times daily. Patients in the treatment group were po administered with Zhongtong'an Capsules on the basis of the control group, 2 grains/time, three times daily. Patients in two groups were treated for 10 d. After treatment, the clinical efficacies were evaluated, and GI scores, PLI scores, and BOP in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 80.00% and 95.00%, respectively, and there was difference between two groups (P<0.05). After treatment, GI scores, PLI scores, and BOP in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the periodontal indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Zhongtong'an Capsules combined with Cydiodine Buccal Tablets has clinical curative effect in treatment of gingivitis, can improve periodontal indexes of patients, with good safety, which has a certain clinical application value.
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