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[摘要]
目的 探讨复方丹参滴丸联合苯磺酸左旋氨氯地平片治疗冠心病心绞痛的临床疗效。方法 选取2015年4月-2017年4月三二〇一医院收治的慢性冠心病心绞痛患者120例为研究对象,随机将所有研究对象分为对照组和治疗组,每组各60例。对照组患者口服苯磺酸左旋氨氯地平片,2.5 mg/次,1次/d。治疗组在对照组治疗的基础上口服复方丹参滴丸,10丸/次,3次/d。两组患者均持续治疗4周。观察两组的临床疗效和心电图疗效,比较两组的临床症状。结果 治疗后,对照组和治疗组的临床疗效总有效率分别为83.33%、95.00%,两组比较差异有统计学意义(P<0.05)。治疗后,对照组和治疗组的心电图疗效总有效率分别为85.00%、96.67%,两组比较差异有统计学意义(P<0.05)。治疗后,两组心绞痛发作次数和心绞痛持续时间均显著降低,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些床症状指标明显低于对照组,两组比较差异具有统计学意义(P<0.05)。结论 复方丹参滴丸联合苯磺酸左旋氨氯地平片治疗冠心病心绞痛具有较好的临床疗效,可改善临床症状,安全性较好,具有一定临床推广应用价值。
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[Abstract]
Objective To investigate the clinical effect of Compound Danshen Dropping Pills combined with Levamlodipine Besylate Tablets in treatment of angina pectoris of coronary heart disease. Methods Patients (120 cases) with angina pectoris of coronary heart disease in San Er Ling Yi Hospital from April 2015 to April 2017 were randomly divided into control and treatment groups, and each group had 60 cases. Patients in the control group were po administered with Levamlodipine Besylate Tablets, 2.5 mg/time, once daily. Patients in the treatment group were po administered with Compound Danshen Dropping Pills on the basis of the control group, 10 pills/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, the clinical efficacies and electrocardiogram efficacies were evaluated, and clinical symptoms in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 83.33% and 95.00%, respectively, and there was difference between two groups (P<0.05). After treatment, the electrocardiogram efficacies in the control and treatment groups were 85.00% and 96.67%, respectively, and there was difference between two groups (P<0.05). After treatment, angina frequency and angina duration of angina pectoris in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the clinical symptoms in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Compound Danshen Dropping Pills combined with Levamlodipine Besylate Tablets has clinical curative effect in treatment of angina pectoris of coronary heart disease, can improve clinical symptoms, with good safety, which has a certain clinical application value.
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