目的 观察二十五味鬼臼丸联合头孢曲松钠治疗慢性盆腔炎的临床疗效。方法 选取中国人民解放军第四五七医院2016年1月-2016年12月收治的慢性盆腔炎患者106例，随机分为对照组和治疗组，每组各53例。对照组患者静脉滴注注射用头孢曲松钠，2 g加入生理盐水250 mL，1次/d；治疗组在对照组的基础上口服二十五味鬼臼丸，5丸/次，2次/d。两组患者均治疗2周。评价两组患者临床疗效，同时比较治疗前后两组患者临床症状评分和炎症因子指标水平。结果 治疗后，对照组临床有效率为73.58%，显著低于治疗组的90.57%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组腹坠痛、白带增多、白带异味和月经异常评分均显著降低，同组比较差异具有统计学意义（P<0.05）；且治疗组上述临床症状评分明显低于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组超敏C反应蛋白（hs-CRP）和白细胞介素-6（IL-6）水平均显著降低，同组比较差异具有统计学意义（P<0.05）；且治疗组比对照组降低更明显（P<0.05）。结论 二十五味鬼臼丸联合头孢曲松钠治疗慢性盆腔炎疗效确切，不良反应较轻，具有一定的临床推广应用价值。

Objective To observe the curative effect of Ershiwuwei Guijiu Pills combined with ceftriaxone sodium in treatment of chronic pelvic inflammatory disease. Methods Patients (106 cases) with chronic pelvic inflammatory disease in 457 Military Hospital of China from January 2016 to December 2016 were randomly divided into control and treatment groups, and each group had 53 cases. Patients in the control group were iv administered with Ceftriaxone Sodium for injection, 2 g added into normal saline 250 mL, once daily. Patients in the treatment group were po administered with Ershiwuwei Guijiu Pills on the basis of the control group, 5 pills/time, twice daily. Patients in two groups were treated for 2 weeks. After treatment, the clinical efficacy was evaluated, and the clinical symptom scores, inflammatory factors levels in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group was 73.58%, which was significantly lower than 90.57% in the treatment group, and there were differences between two groups (P<0.05). After treatment, the abdominal pain, leukorrhagia, leucorrhoea peculiar smell and abnormal menstruation scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the clinical symptom scores in the treatment group after treatment were significantly lower than that in the control group, with significant difference between two groups (P<0.05). After treatment, the hs-CRP and IL-6 levels in two groups were significantly decreased, and there were differences in the same group (P<0.05). And the inflammatory factors levels in the treatment group after treatment were significantly lower than those in the control group (P<0.05). Conclusion Ershiwuwei Guijiu Pills combined with ceftriaxone sodium has obvious curative effect in treatment of chronic pelvic inflammatory disease with less adverse reactions, which has a certain clinical application value.