目的 研究胰胆炎合剂联合注射用乌司他丁治疗急性胰腺炎的临床疗效。方法 选取2017年1月-2017年12月西安交通大学第一附属医院收治的急性胰腺炎患者120例为研究对象，所有患者随机分为对照组和治疗组，每组各60例。对照组静脉滴注注射用乌司他丁，10万单位加入到0.9%氯化钠注射液500 mL中，静滴时间2 h，1次/d。治疗组在对照组治疗的基础上口服胰胆炎合剂，1袋/次，2次/d。两组患者持续治疗7 d。观察两组的临床疗效，比较两组的临床症状恢复时间和生化指标水平。结果 治疗后，对照组和治疗组的总有效率分别为85.00%、96.67%，两组比较差异具有统计学意义（P<0.05）。治疗后，治疗组腹痛缓解时间、胃肠功能恢复时间、血尿淀粉酶正常时间、白细胞计数恢复时间均显著短于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组C反应蛋白（CRP）、白细胞（WBC）、淀粉酶（AMY）和乳酸脱氢酶（LDH）水平均显著降低，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组生化指标水平明显低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 胰胆炎合剂联合注射用乌司他丁治疗急性胰腺炎具有较好的临床疗效，能改善患者临床症状，调节CRP、WBC、AMY和LDH水平，安全性较好，具有一定的临床推广应用价值。

Objective To study the clinical effect of Yidanyan Mixture combined with Ulinastatin for injection in treatment of acute pancreatitis. Methods Patients (120 cases) with acute pancreatitis in the First Affiliated Hospital of Xi'an Jiaotong University from January 2017 to December 2017 were randomly divided into control and treatment groups, and each group had 60 cases. Patients in the control group were iv administered with Ulinastatin for injection, 100 000 unit added into normal saline 500 mL, drop time 2 h, twice daily. Patients in the treatment group were po administered with Yidanyan Mixture on the basis of the control group, 1 bag/time, three times daily. Patients in two groups were treated for 7 d. After treatment, the clinical efficacies were evaluated, and the recovery times of clinical symptoms and the levels of biochemical indexes in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 85.00% and 96.67%, respectively, and there was difference between two groups (P<0.05). After treatment, abdominal pain relief time, gastrointestinal function recovery time, blood urine amylase normal time, and white blood cell count recovery time in the treatment group were significantly shorter than those in the control group, and there was difference between two groups (P<0.05). After treatment, the levels of CRP, WBC, AMY, and LDH in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the biochemical indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Yidanyan Mixture combined with Ulinastatin for injection has clinical curative effect in treatment of acute pancreatitis, can improve the clinical symptoms of patients, and regulate the levels of CRP, WBC, AMY, and LDH, with good safety, which has a certain clinical application value.