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[摘要]
目的 观察胃肠安丸联合蒙脱石散治疗食滞胃肠证急性腹泻的临床疗效。方法 选取2012年5月-2016年10月天津中医药大学第一附属医院收治的食滞胃肠证急性腹泻患者60例,随机分为对照组(29例)和治疗组(31例)。对照组口服蒙脱石散,1袋/次,3次/d;治疗组在对照组的基础上口服胃肠安丸,4丸/次,3次/d,两组患者均连续治疗3 d。评价两组患者临床疗效,同时比较治疗前后两组患者中医证侯评分差异。结果 治疗后,对照组和治疗组临床有效率分别为86.21%和93.55%,两组比较差异无统计学意义。治疗后,两组排便频率、粪便性状、纳呆、脘腹痞满等方面评分显著降低,同组比较差异具有统计学意义(P<0.05)。治疗后,治疗组腹胀、腹痛、嗳气吞酸、舌苔厚腻方面评分明显低于对照组,两组比较差异有统计学意义(P<0.05),同时治疗组在这些方面评分比治疗前显著降低(P<0.05)。治疗后,治疗组纳呆、脘腹痞满方面评分明显低于对照组,两组比较差异具有统计学意义(P<0.05)。结论 胃肠安丸联合蒙脱石散治疗食滞胃肠型急性腹泻在改善中医证侯方面,显示出独特的优势,具有一定的临床推广应用价值。
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[Abstract]
Objective To observe the clinical efficacy of Clinical observation of Weichang'an Pills combined with Montmorillonite Powder in treatment of acute diarrhea of dyspeptic retention gastroenteric disease. Methods Patients (60 cases) with acute diarrhea of dyspeptic retention gastroenteric disease in the First Teaching Hospital of Tianjin University of TCM from May 2012 to October 2016 were randomly divided into control (29 cases) and treatment (31 cases) groups. Patients in the control group were po administered with Montmorillonite Powder, 1 bag/time, three times daily. Patients in the treatment group were po administered with Weichang'an Pills on the basis of the control group, 4 pills/time, three times daily. Patients in two groups were treated for 3 d. After treatment, the clinical efficacy was evaluated, the TCM syndrome scores in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 86.21% and 93.55% respectively, and there were no differences between two groups. After treatment, the defecation frequency, fecal property, anorexia, abdominal fullness and distention scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the abdominal distension and pain, belching and swallowing acid, thick and greasy fru of the tongue scores in the treatment group after treatment were significantly lower than those in the control group, with significant difference between two groups (P<0.05), and these scores in the treatment group after treatment were significantly decreased, and there were differences in the same group (P<0.05). After treatment, the anorexia, abdominal fullness and distention scores in the treatment group after treatment were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Weichang'an Pills combined with Montmorillonite Powder in treatment of acute diarrhea of dyspeptic retention gastroenteric disease has distinctive therapeutic advantage in improving the TCM syndrome, which has a certain clinical application value.
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