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[摘要]
目的 探讨磺胺嘧啶银软膏联合龙血竭胶囊治疗压疮的临床疗效。方法 选取2016年6月—2017年5月东营市第二人民医院收治的压疮患者86例(压疮数118处)为研究对象,按照随机数字表法将全部患者分为对照组(43例,压疮数58处)和治疗组(43例,压疮数60处)。对照组创面外涂生理盐水溶解的龙血竭胶囊,1次/d。治疗组创面外敷磺胺嘧啶银乳膏和龙血竭胶囊混合糊液,1次/d。两组患者均治疗14 d后进行评价。观察两组的临床疗效,比较两组的压疮愈合评估量表(PUSH)评分、视觉模拟评分法(VAS)评分、肉芽形成时间和愈合时间。结果 治疗后,对照组和治疗组的总有效率分别为77.59%、93.33%,两组比较差异有统计学意义(P<0.05)。治疗后,两组PUSH评分和VAS评分均显著降低,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些观察指标明显低于对照组,两组比较差异具有统计学意义(P<0.05)。治疗后,治疗组肉芽形成时间和愈合时间明显短于对照组,两组比较差异有统计学意义(P<0.05)。结论 磺胺嘧啶银软膏联合龙血竭胶囊治疗压疮具有较好的临床疗效,可改善临床症状,缓解疼痛,缩短肉芽形成时间和愈合时间,具有一定的临床推广应用价值。
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[Abstract]
Objective To observe the curative effect of Sulfadiazine Silver Cream combined with Longxuejie Capsules in treatment of pressure sore. Methods Patients (86 cases, 118 pressure ulcers) with pressure sore in the Second People's Hospital of Dongying from June 2016 to May 2017 were randomly divided into the control group (43 cases, 58 pressure ulcers) and the treatment group (43 cases, 60 pressure ulcers). Patients in the control group were coated with Longxuejie Capsules (dissolved in saline) on the wound, once daily. Patients in the treatment group were coated with Sulfadiazine Silver Cream and Longxuejie Capsules mixed paste on the wound, once daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacies were evaluated, and PUSH scores, VAS scores, granulation time and healing time in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 77.59% and 93.33%, respectively, and there was difference between two groups (P < 0.05). After treatment, PUSH scores and VAS scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). After treatment, the granulation time and healing time in the treatment group were significantly shorter than those in the control group, and there was difference between two groups (P < 0.05). Conclusion Sulfadiazine Silver Cream combined with Longxuejie Capsules has clinical curative effect in treatment of pressure sore, can improve clinical symptoms, relieve the pain, and shorten granulation time and healing time, which has a certain clinical application value.
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