目的 探讨注射用重组人促卵泡激素联合枸橼酸氯米芬片治疗多囊卵巢综合征的临床疗效。方法 选取2015年1月—2016年3月新乡市中心医院收治的多囊卵巢综合征患者122例作为研究对象，根据随机表法将所有患者分为对照组和治疗组，每组各61例。对照组口服枸橼酸氯米芬片，100 mg/次，1次/d。治疗组在对照组基础上皮下注射注射用重组人促卵泡激素，75 IU/次，1次/d。两组均连续治疗10 d。观察两组的临床疗效，比较两组的血清激素水平、排卵率和妊娠率。结果 治疗后，对照组和治疗组的总有效率分别为70.49%、91.80%，两组比较差异有统计学意义（P<0.05）。治疗后，两组血清雌二醇（E₂）、孕酮、促卵泡素（FSH）水平明显升高，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组这些观察指标明显高于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，对照组和治疗组排卵率分别为36.07%、62.30%；妊娠率分别为11.48%、27.87%，两组总有效率比较差异具有统计学意义（P<0.05）。结论 注射用重组人促卵泡激素联合枸橼酸氯米芬片治疗多囊卵巢综合征具有较好的临床疗效，能够改善性激素分泌水平，促进排卵功能，具有一定的临床推广应用价值。

Objective To investigate the clinical effect of Recombinant Human Follitropin for injection combined with Clomiphene Citrate Tablets in treatment of polycystic ovary syndrome. Methods Patients (122 cases) with polycystic ovary syndrome in Xinxiang Central Hospital from January 2015 to March 2016 were randomly divided into control and treatment groups, and each group had 61 cases. Patients in the control group were po administered with Clomiphene Citrate Tablets, 100 mg/time, once daily. Patients in the treatment group were sc administered with Recombinant Human Follitropin for injection on the basis of the control group, 75 IU/time, once daily. Patients in two groups were treated for 10 d. After treatment, the clinical efficacies were evaluated, and serum hormone levels, ovulation rates, and pregnancy rates in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 70.49% and 91.80%, respectively, and there was difference between two groups (P < 0.05). After treatment, the levels of E₂, progesterone, and FSH in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P < 0.05). After treatment, the ovulation rates in the control and treatment groups were 36.07% and 62.30%, respectively, and the pregnancy rates in the control and treatment groups were 11.48% and 27.87%, respectively, and there was difference between two groups (P < 0.05). Conclusion Recombinant Human Follitropin for injection combined with Clomiphene Citrate Tablets has clinical curative effect in treatment of polycystic ovary syndrome, can improve sex hormone secretion level and ovulation promoting function, which has a certain clinical application value.