目的 分析郑州市骨科医院口服非甾体抗炎药（NSAIDs）的使用情况，为临床合理用药提供参考。方法 调取2014—2016年口服NSAIDs使用情况的相关信息，对销售金额、用药频度（DDDs）、日均费用（DDC）、药品排序比（B/A）等指标进行统计和分析。结果 口服NSAIDs的销售金额呈逐年上升趋势，依托考昔片、醋氯芬酸缓释片、塞来昔布胶囊和右旋酮洛芬氨丁三醇片的销售金额排前4位；依托考昔片、醋氯芬酸缓释片和塞来昔布胶囊的DDDs稳居前3位；依托考昔片的DDC最高，阿司匹林肠溶片的DDC最低。2014—2016年各药品的B/A值介于0.5～1.5的分别有11、11、10种，总体同步性很好。结论 2014—2016年郑州市骨科医院口服NSAIDs的应用基本合理。

Objective To investigate the utilization of oral non-steroidal anti-inflammatory drugs (NSAIDs) in Zhengzhou Orthopaedic Hospital and provide reference for rational drug use in clinic. Methods Data of NSAIDs in 25 hospitals in Zhengzhou Orthopaedic Hospital from 2014 to 2016 were selected, and consumption sum, frequency of drug use (DDDs), defined daily cost (DDC), and sequence ratio (B/A) of NSAIDs were retrospectively analyzed. Results Consumption sum of oral NSAIDs showed a rising trend year by year, and the top four drugs were still Etoricoxib Tablets, Aceclofenac Sustained-release Tablets, Celecoxib Capsules, and Dexketoprofen Trometamol Tablets. DDDs of Etoricoxib Tablets, Aceclofenac Sustained-release Tablets, and Celecoxib Capsules ranked the top three. DDC of Imrecoxib Tablets ranked the first, while DDC of Aspirin Enteric-coated Tablets ranked the end. The number of drugs whose B/A values between 0.5 to 1.5 was 11, 11, and 10, respectively. The overall synchronization was good. Conclusion The application of oral NSAIDs is basically rational in Zhengzhou Orthopaedic Hospital from 2014 to 2016.