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[摘要]
目的 调查焦作市第二人民医院注射用丹参多酚酸盐的使用情况,为临床合理用药提供参考。方法 回顾性调查焦作市第二人民医院2016年1月-2016年12月使用注射用丹参多酚酸盐的住院病例404份,对其用药原因、用法用量、用药疗程、联合用药、不良反应等进行统计分析。结果 使用注射用丹参多酚酸盐的患者中男性明显多于女性,用药科室主要为心血管内科,构成比高达82.67%,注射用丹参多酚酸盐存在超说明书用药情况,其中既无辨证又无辨病用药者占24.25%,用量不足的构成比为84.65%,超疗程用药占14.85%,溶媒量不足占0.6%,联合用药不当5例,药品不良反应发生率为0.50%。结论 2016年焦作市第二人民医院注射用丹参多酚酸盐的应用基本合理,但还存在不合理情况,应加强其规范使用的管理。
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[Abstract]
Objective To investigate the usage of Salvianolate for injection in the Second People's Hospital of Jiaozuo in 2016, and provide reference for clinical rational use of drugs. Methods Data of inpatients (404 cases) using Salvianolate for injection in the Second People's Hospital from January 2016 to December 2016 were analyzed retrospectively, including medication reasons, usage and dosage, course of treatment, drug combination, and adverse reactions. Results Men using Salvianolate for injection were more than women. The main department was Department of Cardiovascular Medicine, accounting for 82.67%. There was off-label use in Salvianolate for injection. Among them, non-syndrome differentiation and non-disease differentiation accounted for 24.25%. The rate of insufficient use was 84.65%, while over-long treatment course accounted for 14.85%. Insufficient amount of solvent accounted for 0.6%. There were five cases of irrational using about drug combination. The incidence of adverse drug reactions was 0.5%. Conclusion The usage of Salvianolate for injection in the Second People's Hospital of Jiaozuo in 2016 is reasonable on the whole, but there is some unreasonable use, therefore the management of its standardization is should be strengthened.
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