目的 研究心脉隆注射液联合磷酸肌酸钠治疗慢性心力衰竭的临床效果。方法 选取2014年10月-2017年1月延安市人民医院收治的慢性心力衰竭患者115例，随机分为对照组（57例）和治疗组（58例）。对照组静脉滴注注射用磷酸肌酸钠，1 g加入5%葡萄糖溶液250 mL，2次/d；治疗组在对照组的基础上静脉滴注心脉隆注射液，5 mg/kg加入生理盐水250 mL，2次/d。两组患者均治疗14 d。评价两组患者临床疗效，同时比较治疗前后两组患者心功能指标、脑钠肽（BNP）水平和6 min步行距离。结果 治疗后，对照组的临床总有效率为75.8%，显著低于治疗组的90.5%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者左心室舒张末期内径（LVEDD）、左心室收缩末期内径（LVESD）均显著降低，左室射血分数（LVEF）显著上升，同组比较差异具有统计学意义（P<0.05）；且治疗组患者心功能指标改善程度显著优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者BNP均显著降低，6 min步行距离显著增加，同组比较差异具有统计学意义（P<0.05）；且治疗组患者BNP水平和6 min距离优于对照组，两组比较差异具有统计学意义（P<0.05）。结论 心脉隆注射液联合磷酸肌酸钠治疗慢性心力衰竭临床疗效较好，显著改善左心室功能，具有一定的临床推广应用价值。

Objective To explore the clinic effect of Xinmailong Injection combined with creatine phosphate sodium in treatment of chronic heart failure. Methods Patients (115 cases) with chronic heart failure in Yan'an People's Hospital from October 2014 to January 2017 were randomly divided into control (57 cases) and treatment (58 cases) groups. Patients in the control group were iv administered with Creatine Phosphate Sodium for injection, 1 g added into 5% glucose solution 250 mL, twice daily. Patients in the treatment group were iv administered with Xinmailong Injection on the basis of the control group, 5 mg/kg added into normal saline 250 mL, twice daily. Patients in two groups were treated for 14 d. After treatment, the clinical efficacy was evaluated, and cardiac function index, BNP level and 6 min walking distance in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group was 75.8%, which was significantly lower than 90.5% in the treatment group, and there were differences between two groups (P<0.05). After treatment, the LVEDD, LVESD in two groups were significantly decreased, but LVEF was significantly increased, and there were differences in the same group (P<0.05). And the improvement of cardiac function index in the treatment group was significantly better than those in the control group, with significant difference between two groups (P<0.05). After treatment, the BNP in two groups were significantly decreased, but 6 min walking distance was significantly increased, and the difference was statistically significant in the same group (P<0.05). And the BNP level and 6 min walking distance in the treatment group was significantly better than those in the control group, with significant difference between two groups (P<0.05). Conclusion Xinmailong Injection combined with creatine phosphate sodium can significantly improve the efficiency and the left ventricular function in treatment of chronic heart failure, which has a certain clinical application value.