目的 评价郑州市骨科医院麻醉性镇痛药物的使用情况，为临床合理用药提供参考。方法 调取2014-2016年麻醉性镇痛药物使用情况的相关信息，对用药金额、用药频度（DDDs）、日限定费用（DDC）、药品排序比（B/A）等指标进行统计和分析。结果 麻醉性镇痛药物的销售金额呈逐年上升趋势，地佐辛注射液、枸橼酸舒芬太尼注射液（0.05 mg）、注射用盐酸瑞芬太尼、盐酸羟考酮注射液和氨酚双氢可待因片依次排前5位；氨酚双氢可待因片、枸橼酸舒芬太尼注射液（0.05 mg）、注射用盐酸瑞芬太尼、地佐辛注射液、盐酸曲马多缓释片的DDDs稳居前5位。地佐辛注射液的DDC最高，盐酸吗啡注射液的DDC最低。2016年氨酚双氢可待因片和枸橼酸舒芬太尼注射液（0.05 mg）的B/A相较于前两年变化较大。结论 郑州市骨科医院麻醉性镇痛药物的应用基本合理，但个别药物费用较高，值得关注。

Objective To investigate the utilization of narcotic analgesics in Zhengzhou Orthopaedics Hospital, and provide reference for rational drug use in clinic. Methods The data of utilization of narcotic analgesics in Zhengzhou Orthopaedics Hospital from 2014 to 2016 were selected, and consumption sums, frequency of drug use (DDDs), defined daily cost (DDC), and drug sequence ratio (B/A) were calculated and analyzed. Results Consumption sum of narcotic analgesics showed a rising trend year by year, and the top five were still Dezocine Injection, Sufentanil Citrate Injection (0.05 mg), Remifentanil Hydrochloride for injection, Oxycodone Hydrochloride Injection, and Aminophen Bihydrocodeine Tablets. DDDs of Aminophen Bihydrocodeine Tablets, Sufentanil Citrate Injection (0.05 mg), Remifentanil Hydrochloride for injection, Dezocine Injection, and Tramadol Hydrochloride Sustained Release Tablets ranked the top 5. DDC of Dezocine Injection was the highest, and DDC of Morphine Hydrochloride Injection was the lowest. B/A of Aminophen Bihydrocodeine Tablets and Sufentanil Citrate Injection (0.05 mg) in 2016 were changed more compared with the last two years. Conclusion The application of narcotic analgesics is basically rational in Zhengzhou Orthopaedics Hospital, but the cost of certain narcotic analgesics is higher, which is worthy of concern.