目的 观察穴位注射腺苷钴胺治疗腰椎间盘突出症的临床疗效。方法 选取2015年12月-2016年11月到天津市南开医院康复科就诊的腰椎间盘突出症患者58例，随机分为对照组和治疗组，每组各29例。对照组患者给予电针治疗，5次/周，10次为1个疗程。治疗组在对照组治疗基础上给予穴位注射注射用腺苷钴胺，5次/周，10次为1个疗程。两组患者均连续治疗2个疗程。观察两组的临床疗效，比较两组治疗前后JOA评分、VAS评分、Oswestry功能障碍指数（ODI）的变化情况。结果 治疗后，对照组和治疗组的总有效率分别为82.76%、93.10%，两组比较差异具有统计学意义（P<0.05）。治疗1、2个疗程后，两组患者JOA主观症状评分、JOA临床体征评分均较治疗前显著升高，VAS评分、ODI指数均显著降低，同组治疗前后比较差异具有统计学意义（P<0.05）；治疗1个疗程后，治疗组JOA主观症状评分高于对照组，VAS评分、ODI指数低于对照组；治疗2个疗程后，治疗组JOA主观症状评分、JOA临床体征评分高于对照组，VAS评分低于对照组，两组比较差异具有统计学意义（P<0.05）。结论 穴位注射腺苷钴胺治疗腰椎间盘突出症具有较好的临床疗效，可显著改善患者临床症状，具有一定的临床推广应用价值。

Objective To study the clinical effect of acupoint injection of cobamamide in treatment of lumbar disc herniation. Methods Patients (58 cases) with lumbar disc herniation in Tianjin Nankai Hospital from December 2015 to November 2016 were randomly divided into control and treatment groups, and each group had 29 cases. Patients in the control group were iv administered with electroacupuncture treatment, five times one week, and 10 times were as one course of treatment. Patients in the treatment group were given acupuncture injection with Cobamamide for injection on the base of the control group, five times one week, and 10 times were as one course of treatment. Patients in two groups were treated for 2 courses of treatment. After treatment, the clinical efficacy was evaluated, and the changes of JOA scores, VAS scores, and ODI in two groups were compared. Results After treatment, the clinical efficacy in the control and treatment groups were 82.76% and 93.10%, respectively, and there were differences between two groups (P<0.05). After treatment for 1 and 2 courses, JOA subjective symptoms score and JOA clinical signs score in two groups were significantly increased, but VAS scores, and ODI were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment for 1 course, JOA subjective symptoms score in the treatment group was higher than that in the control group, but VAS scores and ODI were lower than those in the control group. After treatment for 1 course, JOA subjective symptoms score and JOA clinical signs score in the treatment group were higher than those in the control group, but VAS scores was lower than that in the control group, and there was difference between two groups (P<0.05). Conclusion Acupoint injection of cobamamide has a significant effect in treatment of lumbar disc herniation, and can significantly improve the clinical symptoms, which has a certain clinical application value.