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[摘要]
目的 探讨双歧杆菌三联活菌散联合醒脾养儿颗粒治疗婴幼儿肺炎继发性腹泻的临床疗效。方法 选取淮安市淮安医院2015年1月-2017年1月收治的婴幼儿肺炎继发性腹泻患儿108例,随机分成对照组(54例)与治疗组(54例)。对照组患儿口服醒脾养儿颗粒,0~1岁1 g/次,2次/d; 1~2岁2 g/次,2次/d; 2~3岁4 g/次,2次/d。治疗组在对照组基础上口服双歧杆菌三联活菌散,0~1岁0.5 g/次,3次/d; 1~3岁1 g/次,3次/d。两组患儿均连续治疗7 d。评价两组患儿临床疗效,同时比较治疗前后两组患儿症状体征消失时间和大便次数。结果 治疗后,对照组患儿总有效率为75.93%,显著低于治疗组的90.74%,两组比较差异具有统计学意义(P<0.05)。治疗组循环不良、呕吐和腹泻消失时间比对照组显著缩短,两组比较差异具有统计学意义(P<0.05)。在第3、5、7天治疗组大便次数显著少于对照组,两组比较差异具有统计学意义(P<0.05)。结论 双歧杆菌三联活菌散联合醒脾养儿颗粒治疗婴幼儿肺炎继发性腹泻可有效缓解临床症状体征、提高临床疗效,且安全性高,具有一定的临床推广应用价值。
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[Abstract]
Objective To investigate the clinical effect of Bifid Triple Viable Powder combined with Xingpi Yanger Granules in treatment of secondary diarrhea of infantile pneumonia. Methods Children (108 cases) with secondary diarrhea of pneumonia in Huaian Hospital of Huaian from January 2015 to January 2017 were randomly divided into control (54 cases) and treatment (54 cases) groups. Children in the control group were po administered with Xingpi Yanger Granules, 1 g/time for 0-1 year old children, 2 g/time for 1-2 year old children, 4 g/time for 2-3 year old children, twice daily. Children in the treatment group were po administered with Bifid Triple Viable Powder on the basis of the control group, 0.5 g/time for 0-1 year old children, 1 g/time for 1-3 year old children, three times daily. Children in two groups were treated for 7 d. After treatment, the clinical efficacy was evaluated, and the disappearance time of symptoms and signs, and the frequency of stools in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control group was 75.93%, which was significantly lower than 90.74% in the treatment group, and the difference was statistically significant between two groups (P<0.05). After treatment, the disappearance time of poor circulation, vomit and diarrhea in the treatment group was shorter than that in the control group, with significant difference between two groups (P<0.05). After treatment for 2, 4, and 6 d, the frequency of stools in the treatment group was significantly less than that in the control group, with significant difference between two groups (P<0.05). Conclusion Bifid Triple Viable Powder combined with Xingpi Yanger Granules can effectively alleviate the clinical symptoms and improve clinical efficacy in treatment of secondary diarrhea of infantile pneumonia with high safety, which has a certain clinical application value.
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