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[摘要]
目的 探讨芪骨胶囊联合骨瓜提取物注射液治疗中老年不稳定型桡骨远端骨折的临床疗效。方法 选取2015年10月-2016年12月高唐县人民医院收治的中老年桡骨远端骨折患者116例,随机分为对照组和治疗组,每组各58例。对照组静脉滴注骨瓜提取物注射液,50 mg加入5%葡萄糖溶液250 mL中,1次/d;治疗组在对照组的基础上口服芪骨胶囊,3粒/次,3次/d。两组均持续治疗4周。观察两组的临床疗效,同时比较两组治疗前后VAS评分、肿胀程度及其疼痛缓解、肿胀消除和骨折愈合的时间。结果 治疗后,两组总有效率比较差异不具有统计学意义。治疗1、4周后,两组患者VAS评分和肿胀程度评分均显著降低,同组治疗前后比较差异具有统计学意义(P<0.05);且治疗1周后治疗组的上述评分明显低于对照组,两组比较差异具有统计学意义(P<0.05)。治疗后,治疗组疼痛缓解时间、消肿时间以及骨折愈合时间均较对照组明显缩短,两组比较差异具有统计学意义(P<0.05)。结论 芪骨胶囊联合骨瓜提取物注射液治疗中老年不稳定型桡骨远端骨折能有效减轻患者疼痛和肿胀情况,缩短止痛、消肿以及骨折愈合的时间,具有一定的推广应用价值。
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[Abstract]
Objective To explore the clinical effect of Qigu Capsules combined with Gugua Extractives Injection in treatment of middle-aged and old patients with unstable distal radial fractures. Methods Middle-aged and old patients (116 cases) with unstable distal radial fractures in Gaotang County People's Hospital from October 2015 to December 2016 were randomly divided into control and treatment groups, and each group had 58 cases. The patients in the control group were iv administered with Gugua Extractives Injection, 50 mg added into 5% glucose solution 250 mL, once daily. The patients in the treatment group were given Qigu Capsules on the basis of control group, 3 grains/time, three times daily. The patients in two groups were treated for 4 weeks. After treatment, the clinical efficacy was evaluated, and the VAS and swelling situation scores, and pain relief, swelling, and fracture healing time were compared. Results After treatment, there was no significant difference of the clinical efficacies between the control and treatment groups. After treatment for 1 week, the VAS and swelling situation scores were significantly decreased, and the difference was statistically significant in the same group (P<0.05). After treatment, the scores in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). After treatment, the pain relief, swelling, and fracture healing time were significantly shorter than those in the control group, and there were differences between two groups (P<0.05). Conclusion Qigu Capsules combined with Gugua Extractives Injection in treatment of middle-aged and old patients with unstable distal radial fractures can effectively reduce the pain and swelling, and shorten the time of pain, swelling, and fracture healing, which has a certain clinical application value.
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