目的 探讨健脾生血颗粒联合多糖铁复合物治疗妊娠合并缺铁性贫血的临床疗效。方法 选取2016年1月-2016年10月在海南医学院第一附属医院接受诊治的妊娠合并缺铁性贫血患者96例，根据治疗方案差异分为对照组（48例）和治疗组（48例）。对照组患者口服多糖铁复合物胶囊，2粒/次，1次/d。治疗组在对照组的基础上口服健脾生血颗粒，3袋/次，3次/d。两组患者均连续治疗4周。比较治疗前后两组患者临床疗效，以及血红蛋白（Hb）、红细胞计数（RBC）、血清铁蛋白（SF）和总铁结合力（TIBC）水平变化。结果 治疗后，对照组临床总有效率为81.25%，显著低于治疗组的97.92%，两组比较差异具有统计学意义（P<0.05）。治疗后，两组患者Hb、RBC、SF较同组治疗前均明显升高，TIBC明显降低，同组比较差异具有统计学意义（P<0.05）；且治疗组上述观察指标改善更明显，两组比较差异具有统计学意义（P<0.05）。结论 健脾生血颗粒联合多糖铁复合物治疗妊娠合并缺铁性贫血效果显著，安全性高，具有一定的临床推广应用价值。

Objective To investigate the clinical effect of Jianpi Shengxue Granules combined with polysaccharide iron complex in treatment of iron deficiency anemia in pregnancy. Methods Patients (96 cases) with iron deficiency anemia in pregnancy in the First Affiliated Hospital of Hainan Medical University from January 2016 to October 2016 were divided into control (48 cases) and treatment (48 cases) groups based on different treatments. Patients in the control group were po administered with Iron Polysaccharide Complex Capsules, 2 grains/time, once daily. Patients in the treatment group were po administered with Jianpi Shengxue Granules on the basis of the control group, 3 bags/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, clinical efficacy, and the Hb, RBC, SF, and TIBC levels in two groups before and after treatment was compared. Results After treatment, the clinical efficacy in the control group was 81.25%, which was significantly lower than 97.92% in the treatment group, and there were differences between two groups (P<0.05). After treatment, the Hb, RBC, and SF levels in two groups were significantly increased, but TIBC level in two groups was significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the above observation indexes in the treatment group improved more obvious than those in the control group, with significant difference between two groups (P<0.05). Conclusion Jianpi Shengxue Granules combined with polysaccharide iron complex has remarkable effect in treatment of iron deficiency anemia in pregnancy, which has a certain clinical application value.