鼻咽癌是一种在我国南方地区高发的恶性肿瘤，中晚期患者生存率低，患者放射治疗后易复发。鼻咽癌的治疗仍然是个很大的挑战。药物治疗对中晚期鼻咽癌的治疗至关重要。根据药物的抗肿瘤作用机制，对诱导细胞凋亡、放射增敏、逆转多药耐药性以及分子靶向治疗的抗鼻咽癌药物进行综述，以期对药物开发和应用提供一定的理论依据。

Nasopharyngeal carcinoma (NPC) is a highly prevalent malignant tumor in southern China. It is found a low survival rate and more likely to recur after radiotherapy for patients with advanced nasopharyngeal carcinoma. Treatment of NPC remains one of the big challenges. Medical therapy has been crucial to the treatments of NPC. The drugs of induced apoptosis, radiosensitization, multidrug resistance and molecular target according to the mechanism of action are reviewed in this paper, in order to provide theoretical basis for drug development and use.

福建省自然科学基金资助项目（2017J01141、2017J01142）；福建省科技计划社会发展引导性（重点）（2014Y0051）；福建省省属公益类科研院所基本科研专项（2015R1031-4、2015R1031-1）；福建省卫生与计划生育委员会中医药科研项目（2017FJZYZY101）