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[摘要]
目的 了解贵阳中医学院第一附属医院麻醉药品的使用情况及变化趋势,为临床合理用药提供依据。方法 对2013—2015年贵阳中医学院第一附属医院麻醉药品的用量、销售金额、用药频度(DDDs)、日均药费(DDC)及药品排序比(B/A)等进行统计和分析。结果 2013—2015年共收集麻醉药品处方28 209张,涉及11个品规,4种剂型,销售金额由2013年的42.61万元上升至2014年的62.48万元,降至2015年的51.65万元;麻醉药品的DDDs排序相对稳定,枸橼酸舒芬太尼注射液的DDDs稳居第1位,盐酸羟考酮缓释片、注射用瑞芬太尼、盐酸氯胺酮注射液的DDDs逐年上升,盐酸吗啡注射液、芬太尼透皮贴剂的DDDs均有上升趋势,盐酸麻黄碱注射液、盐酸吗啡缓释片的DDDs下降明显。麻醉药品的DDC均有不同程度的波动,各品种的DDC相差较大。枸橼酸舒芬太尼注射液、枸橼酸芬太尼注射液、盐酸氯胺酮注射液的B/A均为1.00。结论 贵阳中医学院第一附属医院不断加强对麻醉药品的管理,以及药师的积极干预,对麻醉药品的合理应用和规范管理起到了积极有效的作用。
[Key word]
[Abstract]
Objective To investigate the application and tendency of narcotic drugs in the First Affiliated Hospital of Guiyang College of Traditional Chinese Medicine, and to provide reference for rational drug use in clinic. Methods The application of narcotic drugs in the First Affiliated Hospital of Guiyang College of Traditional Chinese Medicine from 2013 to 2015 was analyzed retrospectively. The DDDs and the daily drug cost (DDC) and the ratio of the ranked number of the sales amount of drug (B) and the ranked number of DDDs (A) was analyzed. The use frequency of narcotic drugs, the average daily cost of patients with narcotic drugs, whether the amount of drugs use and the number of people using the narcotic drugs synchronized or not were analyzed. Results There were 28 209 prescriptions of narcotic drugs involving 11 varieties and 4 kinds of dosage forms. Consumption sum rosed from 426.1 thousands in 2013 to 624.8 thousands in 2014, and then decreased to 516.5 thousands in 2015. The sequences of DDDs were relatively stable. DDDs of Sufentanil Citrate Injection ranked first. DDDs of Oxycodone Hydrochloride Prolonged-release Tablets, Remifentanil Hydrochloride for injection, and Ketamine Hydrochloride Injection increased year by year. DDDs of Morphine Hydrochloride Injection and Transdermal fentanyl had a rising trend. DDDs of Ephedrine Hydrochloride Injection and Morphine Hydrochloride Sustained-release Tablets declined significantly. DDC of narcotic drugs had different degrees of volatility. And all varieties of DDC differed greatly. B/A of Sufentanil Citrate Injection, Fentanyl Citrate Injection, and Ketamine Hydrochloride Injection were 1.00. Conclusion Strengthening the management of narcotic drugs and the active intervention of pharmacists play a positive and effective role in the rational use and standardized management of narcotic drugs in the First Affiliated Hospital of Guiyang College of Traditional Chinese Medicine.
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