目的 比较盐酸氨基葡萄糖胶囊与醋氯芬酸片治疗肘关节创伤性关节炎的临床疗效。方法 选取2015年9月—2016年9月在郑州市第一人民医院接受治疗的肘关节创伤性关节炎患者86例，根据治疗方案的不同分为治对照和组疗组，每组各43例。对照组口服醋氯芬酸片，0.1 g/次，2次/d。治疗组口服盐酸氨基葡萄糖胶囊，0.75 g/次，2次/d。两组患者均连续治疗6周。观察两组的临床疗效，比较两组的血清学指标、美国特种外科医院膝关节（HSS）评分和视觉模拟评分法（VAS）评分。结果 治疗后，对照组和治疗组的总有效率分别为67.44%、88.37%，两组比较差异有统计学意义（P < 0.05）。治疗后，两组血清Dickkopf-1（DKK-1）水平均明显升高，而硬骨素、护骨素（OPG）水平均显著降低，同组治疗前后比较差异有统计学意义（P < 0.05）；且治疗组这些观察指标的改善程度明显优于对照组，两组比较差异具有统计学意义（P < 0.05）。治疗后，两组HSS评分均明显升高，而VAS评分均显著降低，同组治疗前后比较差异有统计学意义（P < 0.05）；且治疗组这些观察指标的改善程度明显优于对照组，两组比较差异具有统计学意义（P < 0.05）。结论 盐酸氨基葡萄糖胶囊治疗肘关节创伤性关节炎的疗效优于醋氯芬酸片，能改善临床症状，调节血清学指标，安全性较好高，具有一定的临床推广应用价值。

Objective To compare the clinical effect between Glucosamine Hydrochloride Capsules and Aceclofenac Tablets in treatment of traumatic arthritis of elbow joint. Methods Patients (86 cases) with traumatic arthritis of elbow joint in the Medical Group of Zhengzhou People's Hospital from September 2015 to September 2016 were enrolled in this study. According to the difference treatment plan, patients were divided into control and treatment groups, and each group had 43 cases. Patients in the control group were po administered with Aceclofenac Tablets, 0.1 g/time, twice daily. Patients in the treatment group were po administered with Glucosamine Hydrochloride Capsules, 0.75 g/time, twice daily. Patients in two groups were treated for 6 weeks. After treatment, the clinical efficacies were evaluated, and serological indexes, HSS scores and VAS scores in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 67.44% and 88.37%, respectively, and there was difference between two groups (P < 0.05). After treatment, the levels of DKK-1 in two groups were significantly increased, but the levels of sclerostin and OPG in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). After treatment, the HSS scores in two groups were significantly increased, but the VAS scores in two groups were significantly decreased, and the difference was statistically significant in the same group (P < 0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P < 0.05). Conclusion The clinical curative effect of Glucosamine Hydrochloride Capsules in treatment of traumatic arthritis of elbow joint was better than that of Aceclofenac Tablets, can improve clinical symptoms, and regulate serological indexes, with good safety, which has a certain clinical application value.