目的 探讨复方玄驹胶囊联合醋酸曲普瑞林注射液治疗多囊卵巢综合征不孕症的临床疗效。方法 选取2015年5月-2016年5月在信阳市中心医院接受治疗的多囊卵巢综合征不孕症患者80例，按照治疗方法的差别分成对照组和治疗组，每组各40例。对照组皮下注射醋酸曲普瑞林注射液，于月经周期第2天开始，500 μg/次，1次/d，连续治疗7 d，然后变为维持量100 μg/次，1次/d。治疗组在对照组基础上口服复方玄驹胶囊，3粒/次，3次/d。两组患者均治疗4周。观察两组的临床疗效，比较两组的性激素、血管内皮生长因子（VEGF）、肝细胞生长因子（HGF）水平。结果 治疗后，对照组和治疗组的总有效率分别为82.5%、97.5%，两组比较差异有统计学意义（P<0.05）。治疗后，两组血清促黄体生成素（LH）和睾酮（T）水平均显著下降，而卵泡刺激素（FSH）水平均显著上升，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组这些观察指标的改善程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。治疗后，两组血清VEGF、HGF水平均明显降低，同组治疗前后比较差异有统计学意义（P<0.05）；且治疗组这些观察指标的下降程度明显优于对照组，两组比较差异具有统计学意义（P<0.05）。结论 复方玄驹胶囊联合醋酸曲普瑞林注射液治疗多囊卵巢综合征不孕症具有较好的临床疗效，可明显改善性激素水平，降低血清VEGF和HGF水平，具有一定的临床推广应用价值。

Objective To investigate the clinical effect of Compound Xuanju Capsules combined with Triptorelin Acetate Injection in treatment of polycystic ovary syndrome with infertility. Methods Infertile patients (80 cases) with polycystic ovary syndrome in Xinyang Central Hospital from May 2015 to May 2016 were enrolled in this study. According to the difference treatment plan, patients were randomly divided into control and treatment groups, and each group had 40 cases. Patients in the control group were subcutaneous injection administered with Triptorelin Acetate Injection, at the second days of menstruation, 500 μg/time, once daily, continuous treatment for 7 d, then change to maintenance dose of 100 μg/time, once daily. Patients in the treatment group were po administered with Compound Xuanju Capsules on the basis of the control group, 3 grains/time, three times daily. Patients in two groups were treated for 4 weeks. After treatment, the clinical efficacies were evaluated, and the levels of sex hormone, VEGF, and HGF in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 82.5% and 97.5%, respectively, and there was difference between two groups (P<0.05). After treatment, the levels of LH and T in two groups were significantly decreased, but the levels of FSH in two groups significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). After treatment, the levels of VEGF and HGF in two groups were significantly decreased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly lower than those in the control group, with significant difference between two groups (P<0.05). Conclusion Compound Xuanju Capsules combined with Triptorelin Acetate Injection has clinical curative effect in treatment of polycystic ovary syndrome with infertility, can improve sex hormone level, and decrease the levels of VEGF and HGF in serum, which has a certain clinical application value.