[关键词]
[摘要]
目的 探讨肺力咳合剂联合氨茶碱治疗儿童支气管哮喘的临床疗效。方法 选取2014年12月-2016年2月在河南省商城县人民医院接受治疗的支气管哮喘患儿76例,随机分成对照组和治疗组,每组各38例。对照组口服氨茶碱片,2~3 mg/kg,2~3次/d。治疗组在对照组的基础上口服肺力咳合剂,≤7岁患者,10 mL/次;7~14岁患者,15 mL/次,均为3次/d。两组患儿连续治疗3个月。比较两组患儿治疗前后临床疗效、第1秒用力呼气末容积(FEV1)和用力呼气流量(PEF)改变。结果 治疗后,对照组总有效率为78.95%,显著低于治疗组的92.10%,两组总有效率比较差异有统计学意义(P<0.05)。治疗后,两组患儿FEV1、PEF显著升高,同组治疗前后比较差异具有统计学意义(P<0.05);且治疗组患儿FEV1和PEF水平高于对照组,两组比较差异具有统计学意义(P<0.05)。结论 肺力咳合剂联合氨茶碱治疗支气管哮喘的疗效显著,安全性较好,具有一定的临床推广应用价值。
[Key word]
[Abstract]
Objective To explore the curative effect of Feilike Mistura combined with aminophylline in treatment of children with bronchial asthma. Methods Children (76 cases) with bronchial asthma in Shangcheng County People's Hospital from December 2014 to February 2016 were randomly divided into control and treatment groups, and each group had 38 cases. Children in the control group were po administered with Aminophylline Tablets, 2-3 mg/kg, 2-3 times daily. Children in the treatment group were po administered with Feilike Mistura on the basis of the control group, 10 mL/time for ≤7 years old children, 15 mL/time for 7-14 years old children, three times daily. Children in two groups were treated for 3 months. After treatment, the clinical efficacy, FEV1 and PEF in two groups before and after treatment were compared. Results After treatment, the clinical efficacy in the control was 78.95%, which was significantly lower than 92.10% in the treatment group, and there was difference between two groups (P<0.05). After treatment, FEV1 and PEF in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the FEV1 and PEF in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P<0.05). Conclusion Feilike Mistura combined with aminophylline has significant effect in treatment of children with bronchial asthma, which has good safety and certain clinical application value.
[中图分类号]
[基金项目]