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[摘要]
目的 探究灯银脑通胶囊联合脑心通胶囊治疗脑梗死恢复期的临床疗效。方法 选取2013年1月-2016年1月在天津中医药大学第一附属医院接受治疗的脑梗死恢复期患者85例,随机分为对照组(43例)和治疗组(42例)。对照组口服脑心通胶囊,3粒/次,3次/d。治疗组在对照组基础上口服灯银脑通胶囊,3粒/次,3次/d。两组患者均治疗3个月。观察两组的临床疗效,比较两组的美国国立卫生研究院卒中量表(NIHSS)评分、Barthel指数评分和生活质量的情况。结果 治疗后,对照组和治疗组的总有效率分别为60.47%、80.95%,两组比较差异有统计学意义(P<0.05)。治疗后,两组NIHSS评分均明显降低,而Barthel指数评分均显著升高,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些观察指标的改善程度明显优于对照组,两组比较差异具有统计学意义(P<0.05)。治疗后,两组生理功能(PF)、生理职能(RP)、情感职能(RE)、社会功能(SF)、躯体疼痛(BP)、机体活力(VT)、精神健康(MH)和总体健康(GH)评分均显著升高,同组治疗前后比较差异有统计学意义(P<0.05);且治疗组这些观察指标的升高程度明显优于对照组,两组比较差异具有统计学意义(P<0.05)。结论 灯银脑通胶囊联合脑心通胶囊治疗脑梗死恢复期具有较好的临床疗效,能明显改善神经功能和生活能力,提高生活质量,具有一定的临床推广应用价值。
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[Abstract]
Objective To explore the clinical effect of Dengyin Naotong Capsules combined with Naoxintong Capsules in treatment of convalescence cerebral infarction. Methods Patients (85 cases) with convalescence cerebral infarction in First Teaching Hospital of Tianjin University of Traditional Chinese Medicine from January 2013 to January 2016 were randomly divided into control group (43 cases) and treatment group (42 cases). Patients in the control group were po administered with Naoxintong Capsules, 3 grains/time, three times daily. Patients in the treatment group were po administered with Dengyin Naotong Capsules on the basis of the control group, 3 grains/time, three times daily. Patients in two groups were treated for 3 months. After treatment, the clinical efficacies were evaluated, and NIHSS scores, Barthel index scores and quality of life in two groups were compared. Results After treatment, the clinical efficacies in the control and treatment groups were 60.47% and 80.95%, respectively, and there was difference between two groups (P<0.05). After treatment, NIHSS scores in two groups were significantly decreased, but Barthel index scores in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly better than those in the control group, with significant difference between two groups (P<0.05). After treatment, the scores of PF, RP, RE, SF, BP, VT, MH, and GH in two groups were significantly increased, and the difference was statistically significant in the same group (P<0.05). And the observational indexes in the treatment group were significantly higher than those in the control group, with significant difference between two groups (P<0.05). Conclusion Dengyin Naotong Capsules combined with Naoxintong Capsules has clinical curative effect in treatment of convalescence cerebral infarction, can significantly improve nerve function and life ability, and increase quality of life, which has a certain clinical application value.
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