目的 对4-甲磺酰基苯乙酸的合成工艺进行改进，使其更利于工业化生产。方法 以4-甲磺酰基苯乙酮为起始原料，在硅胶固载氟硼酸（HBF₄·SiO₂）的催化下，合成2-（4-（甲磺酰基）苯基）-1-吗啉代乙硫醇，再经水解得到4-甲磺酰基苯乙酸。结果 制得的4-甲磺酰基苯乙酸质量分数为99.8%，总收率约75%。结论 改进后的工艺原料便宜易得，反应温度低，时间短，操作简单，更适用于4-甲磺酰基苯乙酸工业化生产。

Objective To study the improved method for synthesis of 4-methylsulphonylbenzoic acid, so as to provide more suitable technology for industrial production. Methods 4-Methyl sulfonyl acetophenone was used as starting material to synthesize 2-(4-(methylsulfonyl) phenyl)-1-morpholinoethanethione by the catalysis of HBF₄·SiO₂ (fluoroboricacid was supported on SiO₂), and 4-methylsulphonyl-benzoic acid was obtained by hydrolysis reaction. Results The target compound was synthesized. The purity of 4-methylsulphonylbenzoic acid was 99.8% and the total yield was 75%. Conclusion The improved method of synthesis has the advantages of low material cost, short reaction time, low reaction temperature, and simple operation, and is suitable for industrial production of 4-methylsulphonylbenzoic acid.